Protein: RBM27
RNA-binding protein 27 (RNA-binding motif protein 27)

Gene: RBM27
Organism: Homo sapiens
Interactions: 142
UniProt ID: Q9P2N5

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0008270 - zinc ion binding
GO:0016607 - nuclear speck

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1402623

SRPK1
SRSF protein kinase 1

3

10

High-throughput

0.871

High

1006771

SRPK2
SRSF protein kinase 2

3

10

High-throughput

0.855

High

655360

SFPQ
Splicing factor, proline- and glutamine-rich

1

14

High-throughput

0.691

High

1454731

TNPO3
Transportin-3

1

6

High-throughput

0.691

High

373377

MYC
Myc proto-oncogene protein

3

12

High-throughput

0.640

High

1361706

CHC10
Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial

2

3

High-throughput

0.628

High

1356459

TF3C2
General transcription factor 3C polypeptide 2

1

1

High-throughput

0.618

High

157944

CTRO
Citron Rho-interacting kinase

1

7

High-throughput

0.618

High

170397

AURKA
Aurora kinase A

1

1

High-throughput

0.618

High

401629

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

5

High-throughput

0.618

High

452420

PDIA1
Protein disulfide-isomerase

1

6

High-throughput

0.618

High

473154

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

13

High-throughput

0.618

High

485484

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

20

High-throughput

0.618

High

898011

CDK9
Cyclin-dependent kinase 9

1

6

High-throughput

0.618

High

1152664

ELAV1
ELAV-like protein 1

1

10

High-throughput

0.618

High

1369862

CELF1
CUGBP Elav-like family member 1

1

14

High-throughput

0.618

High

1417079

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

1

High-throughput

0.618

High

1438061

RC3H2
Roquin-2

1

13

High-throughput

0.618

High

1454723

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.618

High

1454729

TRI33
E3 ubiquitin-protein ligase TRIM33

1

7

High-throughput

0.618

High

1446679

LUC7L
Putative RNA-binding protein Luc7-like 1

3

7

High-throughput

0.609

High

165832

TR13B
Tumor necrosis factor receptor superfamily member 13B

3

1

High-throughput

0.604

High

589921

RFA2
Replication protein A 32 kDa subunit

2

6

High-throughput

0.584

High

687735

SYTC
Threonine--tRNA ligase 1, cytoplasmic

2

2

High-throughput

0.584

High

696741

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

4

High-throughput

0.584

High

1145414

RNPS1
RNA-binding protein with serine-rich domain 1

1

13

High-throughput

0.575

High

1437387

LN28A
Protein lin-28 homolog A

1

8

High-throughput

0.575

High

1454726

ZN346
Zinc finger protein 346

1

2

High-throughput

0.575

High

288206

CLC3A
C-type lectin domain family 3 member A

2

1

High-throughput

0.574

High

397121

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

1128134

DHX8
ATP-dependent RNA helicase DHX8

2

7

High-throughput

0.571

High

1227618

A16L1
Autophagy-related protein 16-1

1

10

High-throughput

0.553

High

164120

NDC80
Kinetochore protein NDC80 homolog

1

4

High-throughput

0.536

High

244780

ZC3H1
Zinc finger C3H1 domain-containing protein

1

1

High-throughput

0.536

High

261975

RNH1
Ribonuclease H1

1

1

High-throughput

0.536

High

410500

PRM2
Protamine-2

1

1

High-throughput

0.536

High

471298

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.536

High

958367

ARP2
Actin-related protein 2

1

8

High-throughput

0.536

High

990824

1433Z
14-3-3 protein zeta/delta

1

19

High-throughput

0.536

High

991445

SUMO1
Small ubiquitin-related modifier 1

1

2

High-throughput

0.536

High

1117695

NOG2
Nucleolar GTP-binding protein 2

1

5

High-throughput

0.536

High

1123158

FHL2
Four and a half LIM domains protein 2

1

3

High-throughput

0.536

High

1239684

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

1

High-throughput

0.536

High

1273913

BHA15
Class A basic helix-loop-helix protein 15

1

3

High-throughput

0.536

High

1351069

DDX54
ATP-dependent RNA helicase DDX54

1

16

High-throughput

0.536

High

1368808

EZH1
Histone-lysine N-methyltransferase EZH1

1

10

High-throughput

0.536

High

1390987

THOC1
THO complex subunit 1

1

1

High-throughput

0.536

High

1413570

H2AJ
Histone H2A.J

1

8

High-throughput

0.536

High

1415392

DUS23
Dual specificity protein phosphatase 23

1

1

High-throughput

0.536

High

1434725

IKZF5
Zinc finger protein Pegasus

1

3

High-throughput

0.536

High

1446535

MED4
Mediator of RNA polymerase II transcription subunit 4

1

1

High-throughput

0.536

High

1454730

NGN3
Neurogenin-3

1

3

High-throughput

0.536

High

1454733

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

3

High-throughput

0.536

High

769397

RFA3
Replication protein A 14 kDa subunit

2

5

High-throughput

0.533

High

887287

CEBPA
CCAAT/enhancer-binding protein alpha

1

9

High-throughput

0.527

High

1023634

CYC
Cytochrome c

1

0

High-throughput

0.513

High

1036555

ID2
DNA-binding protein inhibitor ID-2

1

0

High-throughput

0.513

High

1233220

THOC7
THO complex subunit 7

1

0

High-throughput

0.513

High

1252784

RN111
E3 ubiquitin-protein ligase Arkadia

1

0

High-throughput

0.513

High

347384

BAG2
BAG family molecular chaperone regulator 2

1

3

High-throughput

0.489

High

226898

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

1

6

Small-scale

0.479

High

247453

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

6

High-throughput

0.479

High

260562

BRD4
Bromodomain-containing protein 4

1

5

High-throughput

0.479

High

323589

TRI37
E3 ubiquitin-protein ligase TRIM37

1

12

High-throughput

0.479

High

346437

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

9

High-throughput

0.479

High

419250

H2A1B
Histone H2A type 1-B/E

1

8

High-throughput

0.479

High

504992

H2AB2
Histone H2A-Bbd type 2/3

1

9

High-throughput

0.479

High

520418

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

558461

XRCC6
X-ray repair cross-complementing protein 6

1

6

High-throughput

0.479

High

831572

CCNF
Cyclin-F

1

2

High-throughput

0.479

High

854948

RECQ1
ATP-dependent DNA helicase Q1

1

7

High-throughput

0.479

High

879565

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

6

High-throughput

0.479

High

905232

MECP2
Methyl-CpG-binding protein 2

1

3

High-throughput

0.479

High

971224

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

9

High-throughput

0.479

High

980471

H4
Histone H4

1

6

High-throughput

0.479

High

1005197

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.479

High

1024905

VIGLN
Vigilin

1

15

High-throughput

0.479

High

1033803

PO5F1
POU domain, class 5, transcription factor 1

1

4

High-throughput

0.479

High

1067787

EP300
Histone acetyltransferase p300

1

8

High-throughput

0.479

High

1096845

RFA4
Replication protein A 30 kDa subunit

1

6

High-throughput

0.479

High

1097602

CBX3
Chromobox protein homolog 3

1

6

High-throughput

0.479

High

1215877

RC3H1
Roquin-1

1

5

High-throughput

0.479

High

1255908

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.479

High

1276901

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

8

High-throughput

0.479

High

1289327

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

5

High-throughput

0.479

High

1289679

NAA40
N-alpha-acetyltransferase 40

1

4

High-throughput

0.479

High

1290789

ZCH18
Zinc finger CCCH domain-containing protein 18

1

6

High-throughput

0.479

High

1311294

CHERP
Calcium homeostasis endoplasmic reticulum protein

1

6

High-throughput

0.479

High

1311882

DHX40
Probable ATP-dependent RNA helicase DHX40

1

9

High-throughput

0.479

High

1313493

SMC5
Structural maintenance of chromosomes protein 5

1

5

High-throughput

0.479

High

1329918

SIR6
NAD-dependent protein deacylase sirtuin-6

1

3

High-throughput

0.479

High

1351183

SP7
Transcription factor Sp7

1

12

High-throughput

0.479

High

1364642

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

1382852

FUBP1
Far upstream element-binding protein 1

1

13

High-throughput

0.479

High

1393784

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.479

High

1428994

WWTR1
WW domain-containing transcription regulator protein 1

1

14

High-throughput

0.479

High

1431557

VP33B
Vacuolar protein sorting-associated protein 33B

1

2

High-throughput

0.479

High

1434114

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.479

High

1448778

RNC
Ribonuclease 3

1

3

High-throughput

0.479

High

1452447

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

2

High-throughput

0.479

High

1454339

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

4

High-throughput

0.479

High

1454722

NXF1
Nuclear RNA export factor 1

1

1

High-throughput

0.479

High

325145

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

828997

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

1332908

KDF1
Keratinocyte differentiation factor 1

1

0

High-throughput

0.458

High

1352803

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1435396

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1454724

SEPT9
Septin-9

1

0

Small-scale

0.458

High

429037

RLA0
Large ribosomal subunit protein uL10

1

5

High-throughput

0.445

High

430455

JUN
Transcription factor Jun

1

8

High-throughput

0.445

High

538040

HSP7C
Heat shock cognate 71 kDa protein

1

7

High-throughput

0.445

High

584157

FOSL2
Fos-related antigen 2

1

3

High-throughput

0.445

High

686495

RL13
Large ribosomal subunit protein eL13

1

3

High-throughput

0.445

High

765961

BMI1
Polycomb complex protein BMI-1

1

5

High-throughput

0.445

High

809895

RS19
Small ribosomal subunit protein eS19

1

4

High-throughput

0.445

High

985045

RL31
Large ribosomal subunit protein eL31

1

3

High-throughput

0.445

High

1034625

AK17A
A-kinase anchor protein 17A

1

3

High-throughput

0.445

High

1198680

NCBP3
Nuclear cap-binding protein subunit 3

1

1

High-throughput

0.445

High

1337430

SRFB1
Serum response factor-binding protein 1

1

3

High-throughput

0.445

High

1414000

MMTA2
Multiple myeloma tumor-associated protein 2

1

2

High-throughput

0.445

High

1453888

H2AW
Core histone macro-H2A.2

1

9

High-throughput

0.445

High

1454728

RL26L
Ribosomal protein uL24-like

1

1

High-throughput

0.445

High

657699

GCSP
Glycine dehydrogenase

1

1

High-throughput

0.437

High

1327242

FBXL6
F-box/LRR-repeat protein 6

1

2

High-throughput

0.437

High

1339214

NUP35
Nucleoporin NUP35

1

3

High-throughput

0.437

High

1447382

ANLN
Anillin

1

1

High-throughput

0.437

High

1450961

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

1

High-throughput

0.437

High

1454721

GMPR2
GMP reductase 2

1

3

High-throughput

0.437

High

1454725

NUP50
Nuclear pore complex protein Nup50

1

2

High-throughput

0.437

High

1454727

HECD1
E3 ubiquitin-protein ligase HECTD1

1

7

High-throughput

0.437

High

290773

SURF6
Surfeit locus protein 6

1

0

High-throughput

0.426

High

1394355

ZN414
Zinc finger protein 414

1

0

High-throughput

0.426

High

1437541

EAF6
Chromatin modification-related protein MEAF6

1

0

High-throughput

0.426

High

62605

S35F4
Solute carrier family 35 member F4

1

1

High-throughput

0.407

High

1313866

S15A3
Solute carrier family 15 member 3

1

1

High-throughput

0.407

High

1431637

CHST8
Carbohydrate sulfotransferase 8

2

0

High-throughput

0.318

High

49475

TM223
Transmembrane protein 223

1

0

High-throughput

0.279

Low

61060

FUCM
Fucose mutarotase

1

0

High-throughput

0.279

Low

652684

GNLY
Granulysin

1

0

High-throughput

0.279

Low

1417691

TX101
Testis-expressed protein 101

1

0

High-throughput

0.279

Low

1454732

SPCS1
Signal peptidase complex subunit 1

1

0

High-throughput

0.279

Low

1025963

NDP
Norrin

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025