HitPredict

Interactor 1: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Interactor 2: CENPA (P49450)
Histone H3-like centromeric protein A (Centromere autoantigen A) (Centromere protein A) (CENP-A)
Gene: CENPA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.881

The method score is based on:

Property Details
Experiments 28514442, 34079125, 15009096, 16622419
Identification Methods affinity chromatography technology, proximity labelling technology, biochemical, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Histone~Histone, Histone~Histone_H2A_C
Common GO terms GO:0000786 - nucleosome
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005721 - pericentric heterochromatin
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024