Protein: GHITM
Growth hormone-inducible transmembrane protein (Dermal papilla-derived protein 2) (Mitochondrial morphology and cristae structure 1) (MICS1) (Transmembrane BAX inhibitor motif-containing protein 5)

Gene: GHITM
Organism: Homo sapiens
Interactions: 166
UniProt ID: Q9H3K2

Gene Ontology (top 5):
GO:0005262 - calcium channel activity
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005789 - endoplasmic reticulum membrane
GO:0006816 - calcium ion transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1432664

SG196
Protein O-mannose kinase

5

1

High-throughput

0.716

High

1402493

SERC2
Serine incorporator 2

3

1

High-throughput

0.667

High

160834

TOR1B
Torsin-1B

4

0

High-throughput

0.661

High

1247712

SARM1
NAD(+) hydrolase SARM1

3

0

High-throughput

0.655

High

1315625

IZUM1
Izumo sperm-egg fusion protein 1

3

0

High-throughput

0.634

High

320504

TM63A
Mechanosensitive cation channel TMEM63A

2

1

High-throughput

0.628

High

326613

MFN2
Mitofusin-2

2

1

High-throughput

0.628

High

251116

B4GT3
Beta-1,4-galactosyltransferase 3

3

0

High-throughput

0.622

High

1108459

MTX1
Metaxin-1

2

1

High-throughput

0.612

High

937597

CAD13
Cadherin-13

2

1

High-throughput

0.611

High

1432665

FNDC4
Fibronectin type III domain-containing protein 4

3

2

High-throughput

0.609

High

1132580

FXYD3
FXYD domain-containing ion transport regulator 3

2

1

High-throughput

0.606

High

1207620

F209A
Protein FAM209A

2

1

High-throughput

0.606

High

1432672

TM242
Transmembrane protein 242

2

2

High-throughput

0.606

High

722617

CTR1
High affinity cationic amino acid transporter 1

3

1

High-throughput

0.604

High

1293905

VSIG1
V-set and immunoglobulin domain-containing protein 1

3

1

High-throughput

0.604

High

1308971

S22A9
Organic anion transporter 7

3

5

High-throughput

0.604

High

1350067

SPP2B
Signal peptide peptidase-like 2B

3

3

High-throughput

0.604

High

596779

DPEP1
Dipeptidase 1

2

0

High-throughput

0.602

High

732849

GLPK
Glycerol kinase

2

0

High-throughput

0.602

High

748713

CGL
Cystathionine gamma-lyase

2

0

High-throughput

0.602

High

1229923

UQCC6
Ubiquinol-cytochrome c reductase complex assembly factor 6

2

0

High-throughput

0.602

High

1294004

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

2

0

High-throughput

0.602

High

1382112

F162A
Protein FAM162A

2

0

High-throughput

0.602

High

1429321

MFR1L
Mitochondrial fission regulator 1-like

2

0

High-throughput

0.602

High

1430253

5NT3A
Cytosolic 5'-nucleotidase 3A

2

0

High-throughput

0.602

High

260957

RAMP3
Receptor activity-modifying protein 3

2

1

High-throughput

0.601

High

932596

PTN5
Tyrosine-protein phosphatase non-receptor type 5

2

0

High-throughput

0.585

High

50692

HACL2
2-hydroxyacyl-CoA lyase 2

2

0

High-throughput

0.576

High

1380589

IGSF8
Immunoglobulin superfamily member 8

2

0

High-throughput

0.576

High

1432684

ENTP2
Ectonucleoside triphosphate diphosphohydrolase 2

2

0

High-throughput

0.576

High

1249945

LRRN1
Leucine-rich repeat neuronal protein 1

2

1

High-throughput

0.574

High

181433

PGRC2
Membrane-associated progesterone receptor component 2

2

1

High-throughput

0.553

High

1398153

JSPR1
Junctional sarcoplasmic reticulum protein 1

2

1

High-throughput

0.553

High

1350601

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

2

1

High-throughput

0.549

High

186941

GPR37
Prosaposin receptor GPR37

1

5

High-throughput

0.541

High

260798

RAMP2
Receptor activity-modifying protein 2

1

1

High-throughput

0.536

High

296332

CP7B1
Cytochrome P450 7B1

1

1

High-throughput

0.536

High

351965

S1PR4
Sphingosine 1-phosphate receptor 4

1

5

High-throughput

0.536

High

522135

BCL2
Apoptosis regulator Bcl-2

1

4

High-throughput

0.536

High

1083747

MPPA
Mitochondrial-processing peptidase subunit alpha

1

2

High-throughput

0.536

High

1350141

SPP
Signal peptide peptidase

1

3

High-throughput

0.536

High

1372391

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

1

High-throughput

0.536

High

1384763

ARL8A
ADP-ribosylation factor-like protein 8A

1

1

High-throughput

0.536

High

1432675

ARL15
ADP-ribosylation factor-like protein 15

1

1

High-throughput

0.536

High

1432685

SAR1B
Small COPII coat GTPase SAR1B

1

1

High-throughput

0.536

High

562392

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

High-throughput

0.515

High

158318

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.513

High

268938

FCG3B
Low affinity immunoglobulin gamma Fc region receptor III-B

1

0

High-throughput

0.513

High

397706

NU4M
NADH-ubiquinone oxidoreductase chain 4

1

0

High-throughput

0.513

High

406983

THY1
Thy-1 membrane glycoprotein

1

0

High-throughput

0.513

High

535539

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.513

High

711667

3MG
DNA-3-methyladenine glycosylase

1

0

High-throughput

0.513

High

820581

GPV
Platelet glycoprotein V

1

0

High-throughput

0.513

High

959401

RAP1B
Ras-related protein Rap-1b

1

0

High-throughput

0.513

High

962470

RHOA
Transforming protein RhoA

1

0

High-throughput

0.513

High

1015119

ARF5
ADP-ribosylation factor 5

1

0

High-throughput

0.513

High

1022956

EFNB1
Ephrin-B1

1

0

High-throughput

0.513

High

1136364

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.513

High

1248542

LCTL
Lactase-like protein

1

0

High-throughput

0.513

High

1294678

NDUAB
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11

1

0

High-throughput

0.513

High

1384959

CC127
Coiled-coil domain-containing protein 127

1

0

High-throughput

0.513

High

1387009

ORAI1
Calcium release-activated calcium channel protein 1

1

0

High-throughput

0.513

High

1401698

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

0

High-throughput

0.513

High

1432670

PLCE
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon

1

0

High-throughput

0.513

High

1432673

SLTM
SAFB-like transcription modulator

1

0

High-throughput

0.513

High

1432678

NAT8B
N-acetyltransferase 8B

1

0

High-throughput

0.513

High

572472

DRD2
D(2) dopamine receptor

1

3

High-throughput

0.494

High

702845

5HT2C
5-hydroxytryptamine receptor 2C

1

4

High-throughput

0.494

High

720696

AGTR1
Type-1 angiotensin II receptor

1

2

High-throughput

0.494

High

906982

CCR4
C-C chemokine receptor type 4

1

3

High-throughput

0.494

High

1116395

5HT4R
5-hydroxytryptamine receptor 4

1

3

High-throughput

0.494

High

1432668

GPR35
G-protein coupled receptor 35

1

5

High-throughput

0.494

High

929832

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.493

High

1432682

SHLB1
Endophilin-B1

1

0

High-throughput

0.493

High

141789

MFNG
Beta-1,3-N-acetylglucosaminyltransferase manic fringe

1

2

High-throughput

0.489

High

141867

ACKR2
Atypical chemokine receptor 2

1

3

High-throughput

0.489

High

166043

FFAR1
Free fatty acid receptor 1

1

8

High-throughput

0.489

High

226365

SNG1
Synaptogyrin-1

1

1

High-throughput

0.489

High

549887

CD79A
B-cell antigen receptor complex-associated protein alpha chain

1

1

High-throughput

0.489

High

636031

PRPS3
Ribose-phosphate pyrophosphokinase 3

1

1

High-throughput

0.489

High

689859

CD27
CD27 antigen

1

1

High-throughput

0.489

High

733073

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

4

High-throughput

0.489

High

833869

P2RY2
P2Y purinoceptor 2

1

4

High-throughput

0.489

High

835388

VIPR2
Vasoactive intestinal polypeptide receptor 2

1

4

High-throughput

0.489

High

1242933

S39A4
Zinc transporter ZIP4

1

2

High-throughput

0.489

High

1315174

PIANP
PILR alpha-associated neural protein

1

1

High-throughput

0.489

High

1332801

FNDC5
Fibronectin type III domain-containing protein 5

1

2

High-throughput

0.489

High

1339367

B3GN7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7

1

2

High-throughput

0.489

High

414611

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

1361701

CHC10
Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial

1

1

High-throughput

0.479

High

1397163

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

1

High-throughput

0.479

High

1432683

UB2J1
Ubiquitin-conjugating enzyme E2 J1

1

2

High-throughput

0.479

High

1432686

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

1

High-throughput

0.479

High

133796

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

0

High-throughput

0.458

High

137813

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.458

High

292223

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

0

High-throughput

0.458

High

386227

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.458

High

639408

5NTD
5'-nucleotidase

1

0

High-throughput

0.458

High

1389892

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

0

High-throughput

0.458

High

1393689

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1432666

SFXN1
Sideroflexin-1

1

0

High-throughput

0.458

High

595107

KCNA2
Potassium voltage-gated channel subfamily A member 2

1

2

High-throughput

0.445

High

845133

EAA3
Excitatory amino acid transporter 3

1

1

High-throughput

0.445

High

1007385

S35A2
UDP-galactose translocator

1

6

High-throughput

0.445

High

1179032

S35G1
Solute carrier family 35 member G1

1

3

High-throughput

0.445

High

1279084

RIC3
Protein RIC-3

1

1

High-throughput

0.445

High

1348055

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

1

High-throughput

0.445

High

1392714

S39AD
Zinc transporter ZIP13

1

2

High-throughput

0.445

High

1409711

MICU1
Calcium uptake protein 1, mitochondrial

1

2

High-throughput

0.445

High

1430877

METL9
Protein-L-histidine N-pros-methyltransferase

1

1

High-throughput

0.445

High

184027

S22A1
Solute carrier family 22 member 1

1

5

Small-scale

0.439

High

217331

PROM1
Prominin-1

1

0

Small-scale

0.438

High

1255514

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

1432680

B3GN3
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

1

2

High-throughput

0.437

High

1068891

NIPA4
Magnesium transporter NIPA4

1

2

High-throughput

0.407

High

1126004

LRC32
Transforming growth factor beta activator LRRC32

1

1

High-throughput

0.407

High

1139571

S39AE
Metal cation symporter ZIP14

1

2

High-throughput

0.407

High

1242224

NPAL3
NIPA-like protein 3

1

2

High-throughput

0.407

High

1247733

S22AP
Solute carrier family 22 member 25

1

5

High-throughput

0.407

High

1251187

ZNT10
Calcium/manganese antiporter SLC30A10

1

2

High-throughput

0.407

High

1256792

LHPL2
LHFPL tetraspan subfamily member 2 protein

1

1

High-throughput

0.407

High

1348814

S35G2
Solute carrier family 35 member G2

1

5

High-throughput

0.407

High

1350006

SPPL3
Signal peptide peptidase-like 3

1

3

High-throughput

0.407

High

1356810

NEUFC
Neuferricin

1

1

High-throughput

0.407

High

1391461

S35A4
Probable UDP-sugar transporter protein SLC35A4

1

3

High-throughput

0.407

High

1432676

SCN3B
Sodium channel regulatory subunit beta-3

1

2

High-throughput

0.407

High

1432681

S35A3
UDP-N-acetylglucosamine transporter

1

3

High-throughput

0.407

High

332705

LYPD3
Ly6/PLAUR domain-containing protein 3

4

0

High-throughput

0.360

High

611345

PTN1
Tyrosine-protein phosphatase non-receptor type 1

3

0

High-throughput

0.347

High

1322258

GNT2A
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase

3

0

High-throughput

0.347

High

325502

CCNB2
G2/mitotic-specific cyclin-B2

2

0

High-throughput

0.328

High

1292023

TPRA1
Transmembrane protein adipocyte-associated 1

2

0

High-throughput

0.328

High

1316798

SELH
Selenoprotein H

2

0

High-throughput

0.328

High

705992

CD1B
T-cell surface glycoprotein CD1b

2

0

High-throughput

0.318

High

1383470

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

2

0

High-throughput

0.313

High

1399610

OPALI
Opalin

2

0

High-throughput

0.313

High

1432671

EVA1B
Protein eva-1 homolog B

2

0

High-throughput

0.313

High

1432677

SC5A4
Probable glucose sensor protein SLC5A4

2

0

High-throughput

0.313

High

1358024

TM171
Transmembrane protein 171

2

0

High-throughput

0.298

High

488343

PPBI
Intestinal-type alkaline phosphatase

1

0

High-throughput

0.279

Low

641999

MATN1
Matrilin-1

1

0

High-throughput

0.279

Low

916145

NAR1
GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1

1

0

High-throughput

0.279

Low

1129744

MDC1
Mediator of DNA damage checkpoint protein 1

1

0

High-throughput

0.279

Low

1324861

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.279

Low

1336527

LRN4L
LRRN4 C-terminal-like protein

1

0

High-throughput

0.279

Low

1415627

RIOK2
Serine/threonine-protein kinase RIO2

1

0

High-throughput

0.279

Low

1432669

NRN1
Neuritin

1

0

High-throughput

0.279

Low

1432674

PLAT2
Phospholipase A and acyltransferase 2

1

0

High-throughput

0.279

Low

1432679

CAH14
Carbonic anhydrase 14

1

0

High-throughput

0.279

Low

1432667

S52A2
Solute carrier family 52, riboflavin transporter, member 2

1

0

High-throughput

0.269

Low

1279745

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.268

Low

589667

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

696485

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

769159

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1005092

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1005555

GBRE
Gamma-aminobutyric acid receptor subunit epsilon

1

0

High-throughput

0.249

Low

1197708

MIDN
Midnolin

1

0

High-throughput

0.249

Low

1327014

EFC4A
EF-hand calcium-binding domain-containing protein 4A

1

0

High-throughput

0.249

Low

256148

S19A2
Thiamine transporter 1

1

0

High-throughput

0.232

Low

689997

CNTFR
Ciliary neurotrophic factor receptor subunit alpha

1

0

High-throughput

0.232

Low

754097

CD80
T-lymphocyte activation antigen CD80

1

0

High-throughput

0.232

Low

1280814

S35E3
Solute carrier family 35 member E3

1

0

High-throughput

0.232

Low

1313836

S15A3
Solute carrier family 15 member 3

1

0

High-throughput

0.232

Low

1389589

SAAL1
Protein SAAL1

1

0

High-throughput

0.232

Low

1407392

S29A1
Equilibrative nucleoside transporter 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025