HitPredict

Interactor 1: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Interactor 2: FOXA1 (P55317)
Hepatocyte nuclear factor 3-alpha (HNF-3-alpha) (HNF-3A) (Forkhead box protein A1) (Transcription factor 3A) (TCF-3A)
Gene: FOXA1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	25609649
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0000976 - transcription cis-regulatory region binding GO:0003677 - DNA binding GO:0005634 - nucleus and 1 others more... GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 369 Hs			1 472
+	Hs
		260864 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		FOXC1_HUMAN (130-457): 7.84e-49: 177: 31.42
+	Hs
		260845 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		FOXK2_HUMAN (67-472): 2.52e-43: 163: 20.69
+	Hs
		260987 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		FOXB1_HUMAN (159-439): 8.56e-45: 161: 32.74
+	Hs
		555374 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		FOXA1_HUMAN (1-472): 5.65e-93: 291: 100.00
+	Hs
		206797 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		FOXO3_HUMAN (46-459): 2.54e-43: 164: 18.72