HitPredict

Interactor 1: H2AY (O75367)
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (Histone H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205)
Gene: MACROH2A1

Interactor 2: SET (Q01105)
Protein SET (HLA-DR-associated protein II) (Inhibitor of granzyme A-activated DNase) (IGAAD) (PHAPII) (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template-activating factor I) (TAF-I)
Gene: SET

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28242625
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~NAP
Common GO terms	GO:0000785 - chromatin GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 369 Hs			1 290
+	Hs
		260925 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		TSYL5_HUMAN (2-257): 3.11e-86: 265: 32.69
+	Hs
		260812 H2AY_HUMAN (1-369): 6.49e-165: 467: 100.00		NP1L1_HUMAN (2-278): 1.56e-83: 258: 18.13
+	Hs
		555417 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		SET_HUMAN (1-236): 6.45e-89: 268: 100.00
+	Hs
		391771 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		TSYL5_HUMAN (2-257): 3.11e-86: 265: 32.69
+	Hs
		391896 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		TSYL1_HUMAN (44-234): 2.32e-85: 264: 38.74
+	Hs
		555373 H2AX_HUMAN (1-142): 1.07e-65: 206: 60.69		NP1L1_HUMAN (2-278): 1.56e-83: 258: 18.13
+	Hs
		876839 H2A2B_HUMAN (1-125): 5.78e-65: 204: 64.06		NP1L1_HUMAN (2-278): 1.56e-83: 258: 18.13
+	Hs
		391616 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		NP1L1_HUMAN (2-278): 1.56e-83: 258: 18.13
+	Hs
		470307 H2A1_HUMAN (1-126): 1.21e-64: 203: 62.02		NP1L1_HUMAN (2-278): 1.56e-83: 258: 18.13
+	Hs
		876804 H2A2C_HUMAN (1-125): 9.23e-64: 201: 63.28		NP1L1_HUMAN (2-278): 1.56e-83: 258: 18.13
+	Hs
		391863 H2A1B_HUMAN (1-126): 1.27e-64: 203: 62.02		NP1L4_HUMAN (4-242): 5.86e-81: 250: 18.81
+	Hs
		470518 H2A1_HUMAN (1-126): 1.21e-64: 203: 62.02		NP1L4_HUMAN (4-242): 5.86e-81: 250: 18.81
+	Hs
		1087091 H2A2C_HUMAN (1-125): 9.23e-64: 201: 63.28		NP1L4_HUMAN (4-242): 5.86e-81: 250: 18.81
+	Hs
		965382 H2A2C_HUMAN (1-125): 9.23e-64: 201: 63.28		TSPY1_HUMAN (22-250): 2.42e-77: 239: 33.19
+	Rn
		1116238 H2A3_RAT (1-126): 8.92e-65: 203: 62.79		TSPY1_RAT (6-237): 1.91e-71: 225: 30.17
+	Zm
		77220 B4FU52_MAIZE (14-117): 1.52e-41: 144: 71.15		Q8L8G5_MAIZE (3-286): 8.23e-81: 250: 23.70
+	Sc
		392309 H2A2_YEAST (14-123): 1.54e-41: 144: 67.27		NAP1_YEAST (6-286): 9.91e-70: 223: 20.45
+	Sc
		392059 H2A1_YEAST (14-123): 2.85e-41: 143: 67.27		NAP1_YEAST (6-286): 9.91e-70: 223: 20.45