HitPredict

Interactor 1: NSMA (O60906)
Sphingomyelin phosphodiesterase 2 (EC 3.1.4.12) (Lyso-platelet-activating factor-phospholipase C) (Lyso-PAF-PLC) (Neutral sphingomyelinase) (N-SMase) (nSMase) (nSMase1)
Gene: SMPD2

Interactor 2: KLK6 (Q92876)
Kallikrein-6 (EC 3.4.21.-) (Neurosin) (Protease M) (SP59) (Serine protease 18) (Serine protease 9) (Zyme)
Gene: KLK6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 423 Hs			1 244
+	Hs
		261300 NSMA_HUMAN (1-423): 0: 736: 100.00		KLK14_HUMAN (1-244): 4.88e-111: 321: 45.16
+	Hs
		261130 NSMA_HUMAN (1-423): 0: 736: 100.00		KLK7_HUMAN (13-242): 3.04e-104: 303: 40.52
+	Hs
		261314 NSMA_HUMAN (1-423): 0: 736: 100.00		KLK9_HUMAN (19-242): 9.73e-102: 297: 43.48
+	Hs
		261325 NSMA_HUMAN (1-423): 0: 736: 100.00		KLK5_HUMAN (19-243): 6.9e-100: 294: 45.42
+	Hs
		210626 NSMA_HUMAN (1-423): 0: 736: 100.00		KLK10_HUMAN (10-243): 7.3e-56: 181: 38.98