HitPredict

Interactor 1: VAMP4 (O75379)
Vesicle-associated membrane protein 4 (VAMP-4)
Gene: VAMP4

Interactor 2: NSF (P46459)
Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein) (NEM-sensitive fusion protein) (Vesicular-fusion protein NSF)
Gene: NSF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 141 Hs			1 744
+	Hs
		803923 VAMP3_HUMAN (47-119): 2.22e-26: 96.7: 41.10		NSF_HUMAN (1-744): 0: 572: 100.00
+	Hs
		803893 VAMP2_HUMAN (46-122): 9.98e-26: 95.5: 35.07		NSF_HUMAN (1-744): 0: 572: 100.00
+	Hs
		803966 VAMP8_HUMAN (41-120): 1.87e-25: 94.3: 27.50		NSF_HUMAN (1-744): 0: 572: 100.00
+	Hs
		306771 VAMP5_HUMAN (52-118): 5.78e-18: 75.8: 31.34		NSF_HUMAN (1-744): 0: 572: 100.00
+	Dm
		870075 Q7JYX5_DROME (15-138): 4.76e-36: 125: 27.42		NSF2_DROME (5-742): 6.55e-166: 498: 63.21
+	Sc
		578499 SEC22_YEAST (23-133): 3.08e-25: 97: 17.12		SEC18_YEAST (4-721): 5.88e-146: 447: 44.22
+	Sc
		578512 SNC1_YEAST (42-119): 1.06e-23: 90.5: 30.77		SEC18_YEAST (4-721): 5.88e-146: 447: 44.22
+	Hs
		874800 VAMP2_HUMAN (46-122): 9.98e-26: 95.5: 35.07		TERA_HUMAN (146-479): 5.59e-69: 244: 31.05