Protein: CATL2
Cathepsin L2 (EC 3.4.22.43) (Cathepsin U) (Cathepsin V)

Gene: CATL2, CTSV
Organism: Homo sapiens
Interactions: 115
UniProt ID: O60911

Gene Ontology (top 5):
GO:0004197 - cysteine-type endopeptidase activity
GO:0004252 - serine-type endopeptidase activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005764 - lysosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

261581

KNG1
Kininogen-1

4

13

High-throughput

0.892

High

261587

CATL1
Procathepsin L

4

6

High-throughput

0.887

High

261608

CATK
Cathepsin K

3

6

High-throughput

0.861

High

261579

CYTN
Cystatin-SN

2

13

High-throughput

0.811

High

261623

CYTM
Cystatin-M

2

13

High-throughput

0.694

High

261578

CYTC
Cystatin-C

1

13

High-throughput

0.691

High

261580

CYTA
Cystatin-A

1

4

High-throughput

0.691

High

261618

MMRN1
Multimerin-1

3

8

High-throughput

0.667

High

261583

FRIH
Ferritin heavy chain

2

1

High-throughput

0.628

High

261633

DAA19
Dynein axonemal assembly factor 19

2

1

High-throughput

0.628

High

261667

PLK2
Serine/threonine-protein kinase PLK2

3

1

High-throughput

0.609

High

261576

VNN2
Pantetheine hydrolase VNN2

2

0

High-throughput

0.602

High

261582

ANF
Natriuretic peptides A

2

0

High-throughput

0.602

High

261624

ZIC1
Zinc finger protein ZIC 1

2

1

High-throughput

0.574

High

261663

TB22B
TBC1 domain family member 22B

2

3

High-throughput

0.574

High

261666

RFOX1
RNA binding protein fox-1 homolog 1

2

2

High-throughput

0.574

High

261593

SRC
Proto-oncogene tyrosine-protein kinase Src

1

1

High-throughput

0.541

High

261622

PGFRL
Platelet-derived growth factor receptor-like protein

1

2

High-throughput

0.541

High

261574

RENR
Renin receptor

1

1

High-throughput

0.536

High

261585

IFNA4
Interferon alpha-4

1

1

High-throughput

0.536

High

261588

CCL3
C-C motif chemokine 3

1

1

High-throughput

0.536

High

261596

CL3L1
C-C motif chemokine 3-like 1

1

1

High-throughput

0.536

High

261655

TMPSD
Transmembrane protease serine 13

1

3

High-throughput

0.536

High

261677

WIF1
Wnt inhibitory factor 1

1

1

High-throughput

0.536

High

261678

ST14
Suppressor of tumorigenicity 14 protein

1

3

High-throughput

0.536

High

261614

DEF1
Neutrophil defensin 1

1

0

High-throughput

0.513

High

261646

LCFC1
Sperm-egg fusion protein LLCFC1

1

0

High-throughput

0.513

High

261653

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.513

High

261594

BRAF
Serine/threonine-protein kinase B-raf

1

2

High-throughput

0.494

High

261601

APC
Adenomatous polyposis coli protein

1

1

High-throughput

0.494

High

261605

MLH1
DNA mismatch repair protein Mlh1

1

1

High-throughput

0.494

High

261670

MLH3
DNA mismatch repair protein Mlh3

1

1

High-throughput

0.494

High

222336

TSN6
Tetraspanin-6

1

1

High-throughput

0.489

High

226925

LIAS
Lipoyl synthase, mitochondrial

1

1

High-throughput

0.489

High

261573

E2F6
Transcription factor E2F6

1

1

High-throughput

0.489

High

261577

NUDT3
Diphosphoinositol polyphosphate phosphohydrolase 1

1

1

High-throughput

0.489

High

261590

PIM1
Serine/threonine-protein kinase pim-1

1

1

High-throughput

0.489

High

261591

MPRI
Cation-independent mannose-6-phosphate receptor

1

3

High-throughput

0.489

High

261592

ADT3
ADP/ATP translocase 3

1

5

High-throughput

0.489

High

261595

PGFRA
Platelet-derived growth factor receptor alpha

1

1

High-throughput

0.489

High

261598

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

1

High-throughput

0.489

High

261600

CCNC
Cyclin-C

1

1

High-throughput

0.489

High

261602

CCR1
C-C chemokine receptor type 1

1

1

High-throughput

0.489

High

261609

PCP4
Calmodulin regulator protein PCP4

1

1

High-throughput

0.489

High

261610

PTSS1
Phosphatidylserine synthase 1

1

1

High-throughput

0.489

High

261612

STX17
Syntaxin-17

1

1

High-throughput

0.489

High

261613

DSCR6
Protein ripply3

1

1

High-throughput

0.489

High

261616

GABPA
GA-binding protein alpha chain

1

1

High-throughput

0.489

High

261617

ZN154
Zinc finger protein 154

1

1

High-throughput

0.489

High

261625

LRC10
Leucine-rich repeat-containing protein 10

1

1

High-throughput

0.489

High

261628

MRM1
rRNA methyltransferase 1, mitochondrial

1

1

High-throughput

0.489

High

261631

APTX
Aprataxin

1

1

High-throughput

0.489

High

261636

RNF10
E3 ubiquitin-protein ligase RNF10

1

3

High-throughput

0.489

High

261641

TB22A
TBC1 domain family member 22A

1

3

High-throughput

0.489

High

261642

TRI41
E3 ubiquitin-protein ligase TRIM41

1

2

High-throughput

0.489

High

261645

SARAF
Store-operated calcium entry-associated regulatory factor

1

1

High-throughput

0.489

High

261648

TEFM
Transcription elongation factor, mitochondrial

1

1

High-throughput

0.489

High

261651

SH23A
SH2 domain-containing protein 3A

1

3

High-throughput

0.489

High

261659

HES4
Transcription factor HES-4

1

1

High-throughput

0.489

High

261662

ST7
Suppressor of tumorigenicity 7 protein

1

1

High-throughput

0.489

High

261665

KLH11
Kelch-like protein 11

1

1

High-throughput

0.489

High

261669

COPG2
Coatomer subunit gamma-2

1

1

High-throughput

0.489

High

261673

DD19B
ATP-dependent RNA helicase DDX19B

1

1

High-throughput

0.489

High

261584

DPB1
HLA class II histocompatibility antigen, DP beta 1 chain

1

2

High-throughput

0.479

High

261589

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.445

High

261606

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

1

High-throughput

0.439

High

261599

SFPQ
Splicing factor, proline- and glutamine-rich

1

1

High-throughput

0.437

High

261611

RAB28
Ras-related protein Rab-28

1

3

High-throughput

0.437

High

261626

CP135
Centrosomal protein of 135 kDa

1

4

High-throughput

0.437

High

261643

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

261619

SBP1
Methanethiol oxidase

1

0

High-throughput

0.426

High

261640

LRC15
Leucine-rich repeat-containing protein 15

1

0

High-throughput

0.426

High

261652

SYT11
Synaptotagmin-11

1

0

High-throughput

0.426

High

160788

TOR1B
Torsin-1B

1

1

High-throughput

0.407

High

261650

MYCBP
c-Myc-binding protein

1

1

High-throughput

0.407

High

261671

S2513
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

1

5

High-throughput

0.407

High

261620

KI3S1
Killer cell immunoglobulin-like receptor 3DS1

3

0

High-throughput

0.347

High

261658

L2HDH
L-2-hydroxyglutarate dehydrogenase, mitochondrial

3

0

High-throughput

0.347

High

213382

ZSC12
Zinc finger and SCAN domain-containing protein 12

2

0

High-throughput

0.288

High

224064

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

1

0

High-throughput

0.282

High

261586

RB
Retinoblastoma-associated protein

1

0

High-throughput

0.282

High

261603

CTNA1
Catenin alpha-1

1

0

High-throughput

0.282

High

261604

BMR1A
Bone morphogenetic protein receptor type-1A

1

0

High-throughput

0.282

High

261607

DCC
Netrin receptor DCC

1

0

High-throughput

0.282

High

261647

RHG07
Rho GTPase-activating protein 7

1

0

High-throughput

0.282

High

185130

FANCG
Fanconi anemia group G protein

1

0

High-throughput

0.279

Low

229193

G6PT1
Glucose-6-phosphate exchanger SLC37A4

1

0

High-throughput

0.279

Low

261575

MBD4
Methyl-CpG-binding domain protein 4

1

0

High-throughput

0.279

Low

261597

AATC
Aspartate aminotransferase, cytoplasmic

1

0

High-throughput

0.279

Low

261615

COPZ1
Coatomer subunit zeta-1

1

0

High-throughput

0.279

Low

261621

PMVK
Phosphomevalonate kinase

1

0

High-throughput

0.279

Low

261630

TMCO3
Transmembrane and coiled-coil domain-containing protein 3

1

0

High-throughput

0.279

Low

261632

SFR1
Swi5-dependent recombination DNA repair protein 1 homolog

1

0

High-throughput

0.279

Low

261634

NRSN1
Neurensin-1

1

0

High-throughput

0.279

Low

261635

D106A
Beta-defensin 106

1

0

High-throughput

0.279

Low

261638

MYBPP
MYCBP-associated protein

1

0

High-throughput

0.279

Low

261639

CGAT1
Chondroitin sulfate N-acetylgalactosaminyltransferase 1

1

0

High-throughput

0.279

Low

261644

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

0

High-throughput

0.279

Low

261654

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

0

High-throughput

0.279

Low

261657

ZDHC6
Palmitoyltransferase ZDHHC6

1

0

High-throughput

0.279

Low

261660

GALT9
Polypeptide N-acetylgalactosaminyltransferase 9

1

0

High-throughput

0.279

Low

261661

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.279

Low

261664

GINM1
Glycoprotein integral membrane protein 1

1

0

High-throughput

0.279

Low

261668

DTL
Denticleless protein homolog

1

0

High-throughput

0.279

Low

261672

FBX2
F-box only protein 2

1

0

High-throughput

0.279

Low

261674

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.279

Low

261676

RN115
E3 ubiquitin-protein ligase RNF115

1

0

High-throughput

0.279

Low

261629

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.249

Low

261649

RANB9
Ran-binding protein 9

1

0

High-throughput

0.249

Low

261656

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

0

High-throughput

0.249

Low

261637

ARF
Tumor suppressor ARF

1

0

High-throughput

0.238

Low

219574

B2L11
Bcl-2-like protein 11

1

0

High-throughput

0.232

Low

261015

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.232

Low

261627

RL7L
Ribosomal protein uL30-like

1

0

High-throughput

0.232

Low

261675

RT18C
Small ribosomal subunit protein bS18m

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025