Interactor 1: NBN (O60934)
Nibrin (Cell cycle regulatory protein p95) (Nijmegen breakage syndrome protein 1) (hNbs1)
Gene: NBN
Interactor 2: MRE11 (P49959)
Double-strand break repair protein MRE11 (EC 3.1.-.-) (Meiotic recombination 11 homolog 1) (MRE11 homolog 1) (Meiotic recombination 11 homolog A) (MRE11 homolog A)
Gene: MRE11
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 1.00 | 0.994 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 23530059, 10783165, 12679336, 30440001, 30179224, 11062235, 22941933, 18458108, 11238951, 17526493, 34348893, 16982765, 17429352, 36736531, 23912341, 18256278, 16540636, 12607003, 12447395, 19244116 and 23 others
more... |
| Identification Methods | affinity chromatography technology, biochemical, two hybrid, pull down, cross-linking study, anti bait coimmunoprecipitation, tandem affinity purification, coimmunoprecipitation, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Metallophos~Nbs1_C |
| Common GO terms | GO:0000723 - telomere maintenance GO:0000724 - double-strand break repair via homologous recombination GO:0000729 - DNA double-strand break processing GO:0000781 - chromosome, telomeric region GO:0005634 - nucleus and 17 others more... |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
