Interactor 1: MRE11 (Q61216)
Double-strand break repair protein MRE11 (EC 3.1.-.-) (Meiotic recombination 11 homolog 1) (MRE11 homolog 1) (Meiotic recombination 11 homolog A) (MRE11 homolog A) (MmMRE11A)
Gene: MRE11

Interactor 2: NBN (Q9R207)
Nibrin (Cell cycle regulatory protein p95) (Nijmegen breakage syndrome protein 1 homolog)
Gene: NBN

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.817

The method score is based on:

Property Details
Experiments 21884979, 17429352, 18854157
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Metallophos~Nbs1_C
Common GO terms GO:0000724 - double-strand break repair via homologous recombination
GO:0000729 - DNA double-strand break processing
GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
GO:0005657 - replication fork
and 14 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 706
Mm

1 751
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 11Aug2025