HitPredict

Interactor 1: ULK1 (O75385)
Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)
Gene: ULK1

Interactor 2: AMRA1 (Q9C0C7)
Activating molecule in BECN1-regulated autophagy protein 1 (DDB1- and CUL4-associated factor 3)
Gene: AMBRA1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.667

The method score is based on:

Property Details
Experiments 23524951, 20921139, 25438055
Identification Methods affinity chromatography technology, enzymatic study, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000045 - autophagosome assembly
GO:0005737 - cytoplasm
GO:0005741 - mitochondrial outer membrane
GO:0005776 - autophagosome
GO:0005829 - cytosol
and 3 others

more...
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1050
Hs

1 1298
+ Hs
+ Hs
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024