HitPredict

Interactor 1: PR40A (O75400)
Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6)
Gene: PRPF40A

Interactor 2: UBE2K (P61086)
Ubiquitin-conjugating enzyme E2 K (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme K) (Huntingtin-interacting protein 2) (HIP-2) (Ubiquitin carrier protein) (Ubiquitin-conjugating enzyme E2-25 kDa) (Ubiquitin-conjugating enzyme E2(25K)) (Ubiquitin-conjugating enzyme E2-25K) (Ubiquitin-protein ligase)
Gene: UBE2K

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.50	0.464

Property	Details
Experiments	21900206
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 957 Hs			1 200
+	Hs
		263559 PR40A_HUMAN (1-957): 5.9e-97: 328: 100.00		UBE2A_HUMAN (1-151): 4.98e-67: 203: 30.46
+	Hs
		896355 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		UBE2K_HUMAN (1-200): 1.35e-82: 245: 100.00
+	Hs
		125301 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		UBE2K_HUMAN (1-200): 1.35e-82: 245: 100.00
+	Hs
		1294888 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72
+	Hs
		849411 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74
+	Hs
		919827 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		UB2D2_HUMAN (4-154): 7.76e-75: 223: 41.06
+	Hs
		895882 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		UB2D3_HUMAN (4-154): 1.49e-73: 220: 39.74
+	Hs
		849444 WWP1_HUMAN (22-297): 5.32e-15: 81.7: 13.88		UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74
+	Hs
		919860 WWP1_HUMAN (22-297): 5.32e-15: 81.7: 13.88		UB2D2_HUMAN (4-154): 7.76e-75: 223: 41.06
+	Hs
		125262 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74
+	Hs
		895910 WWP1_HUMAN (22-297): 5.32e-15: 81.7: 13.88		UB2D3_HUMAN (4-154): 1.49e-73: 220: 39.74
+	Dm
		854579 SUDX_DROME (80-305): 6.98e-18: 91.4: 13.22		UBCD2_DROME (3-153): 4.47e-68: 209: 41.72
+	Hs
		125335 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		UB2D2_HUMAN (4-154): 7.76e-75: 223: 41.06
+	Hs
		1294835 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		UB2E2_HUMAN (3-153): 3.57e-68: 208: 40.40
+	Hs
		1282329 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		UB2E3_HUMAN (3-153): 8.99e-68: 207: 40.40
+	Hs
		125300 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		UB2D3_HUMAN (4-154): 1.49e-73: 220: 39.74
+	Hs
		851871 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		UB2E1_HUMAN (3-153): 1.87e-66: 203: 39.74
+	Hs
		125655 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		UB2E2_HUMAN (3-153): 3.57e-68: 208: 40.40
+	Hs
		125629 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		UB2E3_HUMAN (3-153): 8.99e-68: 207: 40.40
+	Hs
		125263 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		UB2E1_HUMAN (3-153): 1.87e-66: 203: 39.74