HitPredict

Interactor 1: PR40A (O75400)
Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6)
Gene: PRPF40A

Interactor 2: ARRD3 (Q96B67)
Arrestin domain-containing protein 3 (TBP-2-like inducible membrane protein) (TLIMP)
Gene: ARRDC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	38270169
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 957 Hs			1 414
+	Hs
		808830 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		ARRD3_HUMAN (1-414): 2.2e-149: 431: 100.00
+	Hs
		1285047 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		ARRD3_HUMAN (1-414): 2.2e-149: 431: 100.00
+	Hs
		1285070 WWP1_HUMAN (22-297): 5.32e-15: 81.7: 13.88		ARRD3_HUMAN (1-414): 2.2e-149: 431: 100.00
+	Hs
		1252807 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		ARRD2_HUMAN (1-411): 3.62e-128: 377: 53.16
+	Hs
		1252814 WWP1_HUMAN (22-297): 5.32e-15: 81.7: 13.88		ARRD2_HUMAN (1-411): 3.62e-128: 377: 53.16
+	Hs
		1241904 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		ARRD4_HUMAN (4-411): 1.8e-123: 365: 51.10
+	Hs
		1241917 WWP1_HUMAN (22-297): 5.32e-15: 81.7: 13.88		ARRD4_HUMAN (4-411): 1.8e-123: 365: 51.10
+	Hs
		1294858 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		TXNIP_HUMAN (1-399): 5.09e-112: 335: 40.75
+	Hs
		1327911 WWP1_HUMAN (22-297): 5.32e-15: 81.7: 13.88		TXNIP_HUMAN (1-399): 5.09e-112: 335: 40.75
+	Dm
		1367634 SUDX_DROME (80-305): 6.98e-18: 91.4: 13.22		Q9VI00_DROME (16-412): 5.73e-99: 303: 27.23
+	Hs
		808769 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		ARRD1_HUMAN (3-412): 6.67e-68: 223: 21.43
+	Ce
		1341514 WWP1_CAEEL (140-316): 1.15e-16: 87.1: 17.22		Q9XXI4_CAEEL (13-390): 3.83e-96: 295: 26.91
+	Dm
		1367613 SUDX_DROME (80-305): 6.98e-18: 91.4: 13.22		Q9VHZ7_DROME (9-319): 2.49e-75: 245: 23.90
+	Hs
		686035 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		ARRB2_HUMAN (12-375): 9.8e-71: 230: 12.53
+	Hs
		827260 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		ARRB1_HUMAN (12-377): 6.46e-70: 228: 13.41
+	Hs
		1234600 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		ARRD1_HUMAN (3-412): 6.67e-68: 223: 21.43
+	Mm
		1208049 ITCH_MOUSE (85-297): 1.51e-16: 86.7: 14.55		ARRB2_MOUSE (12-358): 4.46e-69: 225: 12.06
+	Hs
		685815 MYH10_HUMAN (432-957): 1.68e-14: 80.8: 9.98		ARRB2_HUMAN (12-375): 9.8e-71: 230: 12.53
+	Hs
		1234607 WWP1_HUMAN (22-297): 5.32e-15: 81.7: 13.88		ARRD1_HUMAN (3-412): 6.67e-68: 223: 21.43
+	Dm
		1366476 SUDX_DROME (80-305): 6.98e-18: 91.4: 13.22		Q9VGU4_DROME (12-309): 4.75e-62: 210: 22.30