HitPredict

Interactor 1: SRS10 (O75494)
Serine/arginine-rich splicing factor 10 (40 kDa SR-repressor protein) (SRrp40) (FUS-interacting serine-arginine-rich protein 1) (Splicing factor SRp38) (Splicing factor, arginine/serine-rich 13A) (TLS-associated protein with Ser-Arg repeats) (TASR) (TLS-associated protein with SR repeats) (TLS-associated serine-arginine protein) (TLS-associated SR protein)
Gene: SRSF10

Interactor 2: FGFR2 (P21802)
Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)
Gene: FGFR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 262 Hs			1 821
+	Hs
		609611 PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46		FGFR3_HUMAN (10-821): 0: 731: 65.69
+	Hs
		674414 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		UFO_HUMAN (5-818): 3.59e-160: 490: 22.49
+	Hs
		516373 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		UFO_HUMAN (5-818): 3.59e-160: 490: 22.49
+	Hs
		674526 PABP3_HUMAN (2-99): 1.17e-17: 84: 18.37		UFO_HUMAN (5-818): 3.59e-160: 490: 22.49
+	Hs
		266888 SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00		NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04
+	Hs
		384664 SRSF2_HUMAN (4-90): 1.89e-24: 99.3: 45.65		NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04
+	Hs
		384775 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04
+	Hs
		384175 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04