HitPredict

Interactor 1: SRS10 (O75494)
Serine/arginine-rich splicing factor 10 (40 kDa SR-repressor protein) (SRrp40) (FUS-interacting serine-arginine-rich protein 1) (Splicing factor SRp38) (Splicing factor, arginine/serine-rich 13A) (TLS-associated protein with Ser-Arg repeats) (TASR) (TLS-associated protein with SR repeats) (TLS-associated serine-arginine protein) (TLS-associated SR protein)
Gene: SRSF10

Interactor 2: PCBP2 (Q15366)
Poly(rC)-binding protein 2 (Alpha-CP2) (Heterogeneous nuclear ribonucleoprotein E2) (hnRNP E2)
Gene: PCBP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34316707
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 262 Hs			1 365
+	Hs
		951975 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		PCBP2_HUMAN (1-365): 6.73e-117: 345: 100.00
+	Hs
		516531 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		PCBP2_HUMAN (1-365): 6.73e-117: 345: 100.00
+	Mm
		904361 SRS10_MOUSE (1-262): 2.41e-34: 126: 100.00		HNRPK_MOUSE (10-361): 2.75e-76: 244: 26.17
+	Hs
		904192 PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46		HNRPK_HUMAN (10-361): 2.75e-76: 244: 26.17
+	Hs
		903884 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		HNRPK_HUMAN (10-361): 2.75e-76: 244: 26.17
+	Mm
		904238 SRSF3_MOUSE (1-95): 1.17e-25: 100: 35.79		HNRPK_MOUSE (10-361): 2.75e-76: 244: 26.17
+	Mm
		904266 SRSF2_MOUSE (4-90): 1.89e-24: 99.3: 45.65		HNRPK_MOUSE (10-361): 2.75e-76: 244: 26.17
+	Hs
		516439 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		HNRPK_HUMAN (10-361): 2.75e-76: 244: 26.17
+	Mm
		665747 PABP1_MOUSE (2-99): 6.34e-19: 87.9: 17.35		HNRPK_MOUSE (10-361): 2.75e-76: 244: 26.17
+	Hs
		1072063 PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46		PCBP1_HUMAN (93-173): 3.7e-12: 68.7: 28.40
+	Hs
		1031431 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		FUBP3_HUMAN (244-362): 8.21e-15: 77.6: 22.69
+	Mm
		888801 SRSF3_MOUSE (1-95): 1.17e-25: 100: 35.79		PCBP1_MOUSE (93-173): 3.7e-12: 68.7: 28.40
+	Hs
		951974 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		PCBP1_HUMAN (93-173): 3.7e-12: 68.7: 28.40
+	Hs
		516642 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		FUBP3_HUMAN (244-362): 8.21e-15: 77.6: 22.69
+	Hs
		1031417 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		FUBP1_HUMAN (216-362): 1.11e-13: 74.1: 19.73
+	Hs
		884293 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		PCBP3_HUMAN (264-358): 5.07e-11: 65.2: 23.16
+	Hs
		963557 TIAR_HUMAN (5-151): 6.76e-17: 81: 13.91		FUBP2_HUMAN (282-364): 1.14e-16: 83.3: 30.12
+	Sc
		376757 PABP_YEAST (2-98): 4.25e-20: 91: 24.74		PBP2_YEAST (64-255): 1.66e-11: 67.2: 14.80
+	Hs
		516530 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		PCBP1_HUMAN (93-173): 3.7e-12: 68.7: 28.40
+	Xl
		251139 EPABA_XENLA (6-93): 1.45e-17: 83.6: 19.32		IF23A_XENLA (264-362): 3.25e-12: 69.5: 21.00