HitPredict

Interactor 1: SRS10 (O75494)
Serine/arginine-rich splicing factor 10 (40 kDa SR-repressor protein) (SRrp40) (FUS-interacting serine-arginine-rich protein 1) (Splicing factor SRp38) (Splicing factor, arginine/serine-rich 13A) (TLS-associated protein with Ser-Arg repeats) (TASR) (TLS-associated protein with SR repeats) (TLS-associated serine-arginine protein) (TLS-associated SR protein)
Gene: SRSF10

Interactor 2: SNR40 (Q96DI7)
U5 small nuclear ribonucleoprotein 40 kDa protein (U5 snRNP 40 kDa protein) (U5-40K) (38 kDa-splicing factor) (Prp8-binding protein) (hPRP8BP) (U5 snRNP-specific 40 kDa protein) (WD repeat-containing protein 57)
Gene: SNRNP40

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000375 - RNA splicing, via transesterification reactions GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 2 others more... GO:0005829 - cytosol GO:0016607 - nuclear speck
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 262 Hs			1 357
+	Hs
		266949 SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00		WDR5_HUMAN (95-357): 1.45e-83: 258: 25.09
+	Hs
		952150 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		NLE1_HUMAN (2-312): 5.34e-81: 256: 21.45
+	Hs
		903196 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		WDR5_HUMAN (95-357): 1.45e-83: 258: 25.09
+	Hs
		516438 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		WDR5_HUMAN (95-357): 1.45e-83: 258: 25.09
+	Hs
		964033 SRSF2_HUMAN (4-90): 1.89e-24: 99.3: 45.65		POC1B_HUMAN (138-357): 8.3e-64: 211: 22.17
+	Hs
		1288389 PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46		SNR40_HUMAN (143-357): 1.07e-57: 192: 19.73
+	Hs
		952072 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		SNR40_HUMAN (143-357): 1.07e-57: 192: 19.73
+	Hs
		267038 SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00		FBXW7_HUMAN (53-216): 6.52e-28: 116: 27.17
+	Hs
		516554 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		A16L1_HUMAN (32-344): 8.46e-35: 136: 29.87
+	Mm
		665760 PABP1_MOUSE (2-99): 6.34e-19: 87.9: 17.35		A16L1_MOUSE (41-350): 2.91e-34: 134: 29.56
+	Hs
		964042 SRSF2_HUMAN (4-90): 1.89e-24: 99.3: 45.65		FBXW7_HUMAN (53-216): 6.52e-28: 116: 27.17