HitPredict

Interactor 1: SRS10 (O75494)
Serine/arginine-rich splicing factor 10 (40 kDa SR-repressor protein) (SRrp40) (FUS-interacting serine-arginine-rich protein 1) (Splicing factor SRp38) (Splicing factor, arginine/serine-rich 13A) (TLS-associated protein with Ser-Arg repeats) (TASR) (TLS-associated protein with SR repeats) (TLS-associated serine-arginine protein) (TLS-associated SR protein)
Gene: SRSF10

Interactor 2: LUC7L (Q9NQ29)
Putative RNA-binding protein Luc7-like 1 (Putative SR protein LUC7B1) (SR+89)
Gene: LUC7L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006376 - mRNA splice site recognition GO:0050733 - RS domain binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 262 Hs			1 371
+	Hs
		1343078 PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46		LUC7L_HUMAN (1-371): 3.08e-112: 333: 100.00
+	Hs
		1263481 SRS12_HUMAN (1-251): 1.31e-38: 137: 46.33		LC7L2_HUMAN (1-264): 6.79e-82: 256: 84.47
+	Hs
		267102 SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00		LC7L2_HUMAN (1-264): 6.79e-82: 256: 84.47
+	Hs
		1357566 PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46		LC7L2_HUMAN (1-264): 6.79e-82: 256: 84.47
+	Hs
		1031502 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		LC7L2_HUMAN (1-264): 6.79e-82: 256: 84.47
+	Hs
		1329991 PABP3_HUMAN (2-99): 1.17e-17: 84: 18.37		LC7L2_HUMAN (1-264): 6.79e-82: 256: 84.47
+	Sc
		376945 PABP_YEAST (2-98): 4.25e-20: 91: 24.74		LUC7_YEAST (5-248): 8.53e-71: 223: 32.54
+	Dm
		970879 RBP1_DROME (1-85): 1.86e-20: 86.5: 36.05		Q9W3X8_DROME (165-272): 2.25e-21: 96.7: 24.56