Protein: A1Z921
Frazzled, isoform B

Gene: A1Z921, fra
Organism: Drosophila melanogaster
Interactions: 91
UniProt ID: A1Z921

Gene Ontology (top 5):
GO:0001764 - neuron migration
GO:0005042 - netrin receptor activity
GO:0005886 - plasma membrane
GO:0007411 - axon guidance
GO:0007432 - salivary gland boundary specification

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

55056

ABL
Tyrosine-protein kinase Abl

3

13

Small-scale

0.827

High

55065

NETB
Netrin-B

2

13

Small-scale

0.754

High

55049

TRIM9
E3 ubiquitin-protein ligase TRIM9

1

13

Small-scale

0.621

High

55045

A1Z921
Frazzled, isoform B

1

18

Small-scale

0.618

High

55053

O61444
mitogen-activated protein kinase kinase

1

3

Small-scale

0.618

High

55055

RAB7
Ras-related protein Rab7

1

7

Small-scale

0.618

High

55057

LAR
Tyrosine-protein phosphatase Lar

1

18

Small-scale

0.618

High

55058

TORSO
Tyrosine-protein kinase receptor torso

1

17

Small-scale

0.618

High

55059

FAS2
Fasciclin-2

1

19

Small-scale

0.618

High

55063

Q0KIF4
receptor protein-tyrosine kinase

1

12

Small-scale

0.618

High

55070

TOLL7
Toll-like receptor 7

1

11

Small-scale

0.618

High

55072

Q7YZA0
Trio, isoform B

1

6

Small-scale

0.618

High

55124

Q9VZV2
Chitinase 7

1

1

Small-scale

0.553

High

55128

CHI10
Probable chitinase 10

1

3

Small-scale

0.553

High

55130

Q9XZ19
Uncharacterized protein

1

0

Small-scale

0.517

High

55116

Q9VW57
Grasp65

1

1

High-throughput

0.481

High

55047

A1ZAF5
Semaphorin-2A

1

2

Small-scale

0.479

High

55075

Q8IP45
Cullin 3, isoform F

1

1

Small-scale

0.479

High

55088

PLXB
Plexin-B

1

4

Small-scale

0.479

High

55054

FLOT2
Flotillin-2

1

0

Small-scale

0.458

High

55066

Q59DP8
Calcium-transporting ATPase

1

0

Small-scale

0.458

High

55069

Q7K3E2
LD34147p

1

0

Small-scale

0.458

High

55074

Q8IMI5
FI04474p

1

0

Small-scale

0.458

High

55081

HDAC1
Histone deacetylase HDAC1

1

0

Small-scale

0.458

High

55098

NCDN
Neurochondrin homolog

1

0

Small-scale

0.458

High

55125

Q9W185
Very long-chain fatty acid transport protein

1

0

Small-scale

0.458

High

55107

Q9VRI3
Uncharacterized protein

1

1

High-throughput

0.439

High

55118

Q9VXC8
trypsin

1

5

High-throughput

0.439

High

55061

AP3D
AP-3 complex subunit delta

1

3

Small-scale

0.437

High

55067

RHDF1
Inactive rhomboid protein 1

1

1

Small-scale

0.437

High

55068

Q7K148
Proteasome subunit beta

1

1

Small-scale

0.437

High

55073

TRA1
Transcription-associated protein 1

1

1

Small-scale

0.437

High

55082

LDH
L-lactate dehydrogenase

1

2

Small-scale

0.437

High

55084

XPO1
Exportin-1

1

1

Small-scale

0.437

High

55086

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

2

Small-scale

0.437

High

55091

Q9VA67
Jonah 99Fii

1

2

Small-scale

0.437

High

55093

Q9VAY2
Heat shock protein 83

1

1

Small-scale

0.437

High

55097

Q9VG59
Protein VAC14 homolog

1

1

Small-scale

0.437

High

55101

Q9VKC8
FI03495p

1

1

Small-scale

0.437

High

55102

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

2

Small-scale

0.437

High

55105

PSB4
Proteasome subunit beta type-4

1

2

Small-scale

0.437

High

55108

Q9VRV8
Transportin-1

1

1

Small-scale

0.437

High

55111

Q9VUJ1
Proteasome subunit beta

1

1

Small-scale

0.437

High

55119

PP2B3
Serine/threonine-protein phosphatase 2B catalytic subunit 3

1

1

Small-scale

0.437

High

55123

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

3

Small-scale

0.437

High

55129

PSB3
Proteasome subunit beta type-3

1

2

Small-scale

0.437

High

55132

XPO2
Exportin-2

1

2

Small-scale

0.437

High

55064

EWG
DNA-binding protein Ewg

1

0

High-throughput

0.251

Low

55046

CLU
Protein clueless

1

0

Small-scale

0.249

Low

55048

A8DY67
Acetyl-CoA carboxylase, isoform E

1

0

Small-scale

0.249

Low

55050

M9PD70
alkaline phosphatase

1

0

Small-scale

0.249

Low

55051

M9PDI0
Midkine and pleiotrophin 2, isoform D

1

0

Small-scale

0.249

Low

55052

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

0

Small-scale

0.249

Low

55060

PSA2
Proteasome subunit alpha type-2

1

0

Small-scale

0.249

Low

55062

UMPS
Uridine 5'-monophosphate synthase

1

0

Small-scale

0.249

Low

55071

Q7KUJ4
Ecdysone-inducible gene L1, isoform B

1

0

Small-scale

0.249

Low

55076

LBR
Lamin-B receptor

1

0

Small-scale

0.249

Low

55077

Q8STG9
DSec61alpha

1

0

Small-scale

0.249

Low

55078

CSN3
COP9 signalosome complex subunit 3

1

0

Small-scale

0.249

Low

55079

Q8SZ38
RE18076p

1

0

Small-scale

0.249

Low

55080

Q8SZK9
HL04814p

1

0

Small-scale

0.249

Low

55083

FACR3
Putative fatty acyl-CoA reductase CG8306

1

0

Small-scale

0.249

Low

55085

CSN4
COP9 signalosome complex subunit 4

1

0

Small-scale

0.249

Low

55087

KRH2
Krueppel homolog 2

1

0

Small-scale

0.249

Low

55089

CSN7
COP9 signalosome complex subunit 7

1

0

Small-scale

0.249

Low

55090

Q9V9W7
Rough deal

1

0

Small-scale

0.249

Low

55092

Q9VAC4
GEO09167p1

1

0

Small-scale

0.249

Low

55094

Q9VBX7
LD15705p

1

0

Small-scale

0.249

Low

55095

PP4R3
Serine/threonine-protein phosphatase 4 regulatory subunit 3

1

0

Small-scale

0.249

Low

55096

ELP6
Elongator complex protein 6

1

0

Small-scale

0.249

Low

55099

Q9VJ58
Fas-associated factor 2, isoform A

1

0

Small-scale

0.249

Low

55100

Q9VJD4
LD24721p

1

0

Small-scale

0.249

Low

55103

Q9VLC5
aldehyde dehydrogenase

1

0

Small-scale

0.249

Low

55104

Q9VMX4
AT19154p

1

0

Small-scale

0.249

Low

55106

Q9VRE0
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A

1

0

Small-scale

0.249

Low

55109

Q9VS57
RE14391p

1

0

Small-scale

0.249

Low

55110

UBC2M
Nedd8-conjugating enzyme UbcE2M

1

0

Small-scale

0.249

Low

55112

Q9VUZ0
Translocon-associated protein subunit beta

1

0

Small-scale

0.249

Low

55113

Q9VVM2
LP12049p

1

0

Small-scale

0.249

Low

55114

Q9VVU1
Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial

1

0

Small-scale

0.249

Low

55115

LTN1
E3 ubiquitin-protein ligase listerin

1

0

Small-scale

0.249

Low

55117

Q9VW68
(S)-3-amino-2-methylpropionate transaminase

1

0

Small-scale

0.249

Low

55120

Q9VXH5
CG9919-PA

1

0

Small-scale

0.249

Low

55121

Q9VXI3
Endoplasmic reticulum protein 44, isoform C

1

0

Small-scale

0.249

Low

55122

NADE
Glutamine-dependent NAD(+) synthetase

1

0

Small-scale

0.249

Low

55126

ANM7
Protein arginine N-methyltransferase 7

1

0

Small-scale

0.249

Low

55127

Q9W2X6
ATP synthase F(1) complex subunit delta, mitochondrial

1

0

Small-scale

0.249

Low

55131

YIPP
Protein yippee

1

0

Small-scale

0.249

Low

55133

Q9Y0Y5
Coatomer subunit epsilon

1

0

Small-scale

0.249

Low

55134

DHRS7
Dehydrogenase/reductase SDR family protein 7-like

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025