HitPredict

Interactor 1: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Interactor 2: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	34079125, 36089195, 17210640
Identification Methods	proximity labelling technology, far western blotting
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 441 Hs			1 136
+	Hs
		268123 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Hs
		268027 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Dm
		356112 Q9VKD5_DROME (1-440): 2.91e-80: 257: 49.89		H3_DROME (1-136): 6.5e-61: 185: 99.27
+	Hs
		245614 TBL1X_HUMAN (13-441): 1.12e-73: 243: 11.39		H32_HUMAN (1-136): 6.5e-61: 185: 99.27
+	Hs
		935208 TBL1R_HUMAN (4-335): 2.6e-56: 195: 11.40		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		934971 DAW1_HUMAN (292-439): 3.56e-20: 93.8: 13.91		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		934796 TAF5_HUMAN (173-441): 4.8e-16: 82.5: 21.19		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		1074789 TAF5_HUMAN (173-441): 4.8e-16: 82.5: 21.19		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Hs
		935118 THOC3_HUMAN (148-434): 3.97e-16: 81.3: 19.03		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		952358 TAF5_HUMAN (173-441): 4.8e-16: 82.5: 21.19		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		792992 LIS1_HUMAN (332-438): 2.37e-14: 76.5: 18.69		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Hs
		903117 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		903260 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Hs
		903128 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		196999 PRP4_HUMAN (337-437): 3.12e-09: 60.7: 16.51		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Dm
		356077 ESC_DROME (23-226): 5.01e-10: 63: 8.10		H3_DROME (1-136): 6.5e-61: 185: 99.27
+	At
		221393 LUH_ARATH (365-439): 2.54e-09: 61.3: 20.00		H31_ARATH (1-136): 1.67e-60: 184: 97.06
+	Sc
		730872 COPA_YEAST (15-182): 2.3e-11: 68.1: 10.71		CENPA_YEAST (18-134): 2.12e-41: 138: 55.83