Protein: PIPSL
Putative PIP5K1A and PSMD4-like protein (PIP5K1A-PSMD4)

Gene: PIPSL
Organism: Homo sapiens
Interactions: 227
UniProt ID: A2A3N6

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0016308 - 1-phosphatidylinositol-4-phosphate 5-kinase activity
GO:0046854 - phosphatidylinositol phosphate biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

58912

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

1

14

High-throughput

0.575

High

58800

PGTB2
Geranylgeranyl transferase type-2 subunit beta

2

3

High-throughput

0.552

High

58824

ADRM1
Proteasomal ubiquitin receptor ADRM1

2

1

High-throughput

0.552

High

51573

SPD2B
SH3 and PX domain-containing protein 2B

1

3

High-throughput

0.445

High

58755

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

5

High-throughput

0.445

High

58757

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

1

4

High-throughput

0.445

High

58758

RPC1
DNA-directed RNA polymerase III subunit RPC1

1

1

High-throughput

0.445

High

58759

PLD2
Phospholipase D2

1

1

High-throughput

0.445

High

58760

CETN3
Centrin-3

1

2

High-throughput

0.445

High

58761

PER1
Period circadian protein homolog 1

1

2

High-throughput

0.445

High

58764

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

2

High-throughput

0.445

High

58766

CF410
Cilia- and flagella-associated protein 410

1

6

High-throughput

0.445

High

58767

GTPB6
Putative GTP-binding protein 6

1

1

High-throughput

0.445

High

58770

KIF1B
Kinesin-like protein KIF1B

1

2

High-throughput

0.445

High

58776

PSD10
26S proteasome non-ATPase regulatory subunit 10

1

2

High-throughput

0.445

High

58777

RECQ4
ATP-dependent DNA helicase Q4

1

3

High-throughput

0.445

High

58779

MTMR5
Myotubularin-related protein 5

1

8

High-throughput

0.445

High

58783

TNFB
Lymphotoxin-alpha

1

1

High-throughput

0.445

High

58784

DQB1
HLA class II histocompatibility antigen, DQ beta 1 chain

1

1

High-throughput

0.445

High

58785

FRIL
Ferritin light chain

1

3

High-throughput

0.445

High

58786

FRIH
Ferritin heavy chain

1

3

High-throughput

0.445

High

58788

TAU
Microtubule-associated protein tau

1

7

High-throughput

0.445

High

58789

TOP2A
DNA topoisomerase 2-alpha

1

1

High-throughput

0.445

High

58790

KPSH1
Serine/threonine-protein kinase H1

1

6

High-throughput

0.445

High

58793

MERL
Merlin

1

6

High-throughput

0.445

High

58797

KC1E
Casein kinase I isoform epsilon

1

11

High-throughput

0.445

High

58799

NEK4
Serine/threonine-protein kinase Nek4

1

5

High-throughput

0.445

High

58806

RHG01
Rho GTPase-activating protein 1

1

4

High-throughput

0.445

High

58809

KIF1A
Kinesin-like protein KIF1A

1

2

High-throughput

0.445

High

58810

FLII
Protein flightless-1 homolog

1

1

High-throughput

0.445

High

58812

PLD1
Phospholipase D1

1

1

High-throughput

0.445

High

58814

DGKZ
Diacylglycerol kinase zeta

1

1

High-throughput

0.445

High

58815

MTMR1
Phosphatidylinositol-3-phosphate phosphatase MTMR1

1

4

High-throughput

0.445

High

58819

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

2

High-throughput

0.445

High

58823

ITSN1
Intersectin-1

1

1

High-throughput

0.445

High

58826

EMAL3
Echinoderm microtubule-associated protein-like 3

1

4

High-throughput

0.445

High

58834

DEN4C
DENN domain-containing protein 4C

1

5

High-throughput

0.445

High

58838

TTLL5
Tubulin polyglutamylase TTLL5

1

1

High-throughput

0.445

High

58842

C2D1A
Coiled-coil and C2 domain-containing protein 1A

1

4

High-throughput

0.445

High

58850

PHLB2
Pleckstrin homology-like domain family B member 2

1

3

High-throughput

0.445

High

58853

HOOK3
Protein Hook homolog 3

1

4

High-throughput

0.445

High

58856

RB6I2
ELKS/Rab6-interacting/CAST family member 1

1

5

High-throughput

0.445

High

58857

ARL17
ADP-ribosylation factor-like protein 17

1

5

High-throughput

0.445

High

58865

ASPM
Abnormal spindle-like microcephaly-associated protein

1

3

High-throughput

0.445

High

58871

MINK1
Misshapen-like kinase 1

1

1

High-throughput

0.445

High

58872

ARG39
Rho guanine nucleotide exchange factor 39

1

5

High-throughput

0.445

High

58875

CBPC5
Cytosolic carboxypeptidase-like protein 5

1

1

High-throughput

0.445

High

58877

NEDD1
Protein NEDD1

1

3

High-throughput

0.445

High

58879

ARRD2
Arrestin domain-containing protein 2

1

7

High-throughput

0.445

High

58882

UTP15
U3 small nucleolar RNA-associated protein 15 homolog

1

3

High-throughput

0.445

High

58891

KAT2A
Histone acetyltransferase KAT2A

1

11

High-throughput

0.445

High

58902

CHAP1
Chromosome alignment-maintaining phosphoprotein 1

1

4

High-throughput

0.445

High

58905

YTDC1
YTH domain-containing protein 1

1

1

High-throughput

0.445

High

58907

NEK1
Serine/threonine-protein kinase Nek1

1

6

High-throughput

0.445

High

58910

CK5P2
CDK5 regulatory subunit-associated protein 2

1

3

High-throughput

0.445

High

58913

TEP1
Telomerase protein component 1

1

4

High-throughput

0.445

High

58914

VRK1
Serine/threonine-protein kinase VRK1

1

10

High-throughput

0.445

High

58917

SLF1
SMC5-SMC6 complex localization factor protein 1

1

2

High-throughput

0.445

High

58922

TLR10
Toll-like receptor 10

1

1

High-throughput

0.445

High

58925

HELZ2
3'-5' exoribonuclease HELZ2

1

1

High-throughput

0.445

High

58944

MYO5C
Unconventional myosin-Vc

1

3

High-throughput

0.445

High

58949

KLH11
Kelch-like protein 11

1

1

High-throughput

0.445

High

58959

CAMP3
Calmodulin-regulated spectrin-associated protein 3

1

2

High-throughput

0.445

High

58960

E2AK4
eIF-2-alpha kinase GCN2

1

1

High-throughput

0.445

High

58965

HOOK1
Protein Hook homolog 1

1

4

High-throughput

0.445

High

58969

TAOK2
Serine/threonine-protein kinase TAO2

1

4

High-throughput

0.445

High

58971

CBPC1
Cytosolic carboxypeptidase 1

1

1

High-throughput

0.445

High

58972

MOK
MAPK/MAK/MRK overlapping kinase

1

5

High-throughput

0.445

High

58976

MYO5A
Unconventional myosin-Va

1

3

High-throughput

0.445

High

58801

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.426

High

58808

DYH14
Dynein axonemal heavy chain 14

1

0

High-throughput

0.426

High

58827

TPRN
Taperin

1

0

High-throughput

0.426

High

58848

POGZ
Pogo transposable element with ZNF domain

1

0

High-throughput

0.426

High

58851

VASH2
Tubulinyl-Tyr carboxypeptidase 2

1

0

High-throughput

0.426

High

58855

PTOV1
Prostate tumor-overexpressed gene 1 protein

1

0

High-throughput

0.426

High

58870

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.426

High

58876

TDRD7
Tudor domain-containing protein 7

1

0

High-throughput

0.426

High

58883

CE192
Centrosomal protein of 192 kDa

1

0

High-throughput

0.426

High

58884

RPGF6
Rap guanine nucleotide exchange factor 6

1

0

High-throughput

0.426

High

58885

SMCR8
Guanine nucleotide exchange protein SMCR8

1

0

High-throughput

0.426

High

58899

CEP95
Centrosomal protein of 95 kDa

1

0

High-throughput

0.426

High

58900

PRR11
Proline-rich protein 11

1

0

High-throughput

0.426

High

58903

MARK4
MAP/microtubule affinity-regulating kinase 4

1

0

High-throughput

0.426

High

58921

TALD3
Protein TALPID3

1

0

High-throughput

0.426

High

58927

ASPC1
Tether containing UBX domain for GLUT4

1

0

High-throughput

0.426

High

58931

FA83D
Protein FAM83D

1

0

High-throughput

0.426

High

58935

YYAP1
YY1-associated protein 1

1

0

High-throughput

0.426

High

58937

ELP3
Elongator complex protein 3

1

0

High-throughput

0.426

High

58943

DMAP1
DNA methyltransferase 1-associated protein 1

1

0

High-throughput

0.426

High

58947

PDRG1
p53 and DNA damage-regulated protein 1

1

0

High-throughput

0.426

High

58952

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

0

High-throughput

0.426

High

58961

DCDC2
Doublecortin domain-containing protein 2

1

0

High-throughput

0.426

High

58962

AMACR
Alpha-methylacyl-CoA racemase

1

0

High-throughput

0.426

High

58968

FBX10
F-box only protein 10

1

0

High-throughput

0.426

High

58977

TSSC4
U5 small nuclear ribonucleoprotein TSSC4

1

0

High-throughput

0.426

High

58763

TBX1
T-box transcription factor TBX1

1

1

High-throughput

0.407

High

58768

RAD21
Double-strand-break repair protein rad21 homolog

1

1

High-throughput

0.407

High

58769

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

3

High-throughput

0.407

High

58773

CAPON
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

1

3

High-throughput

0.407

High

58775

KDM4A
Lysine-specific demethylase 4A

1

1

High-throughput

0.407

High

58778

LETM1
Mitochondrial proton/calcium exchanger protein

1

1

High-throughput

0.407

High

58781

PCNT
Pericentrin

1

3

High-throughput

0.407

High

58792

SMCA1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1

1

3

High-throughput

0.407

High

58794

CETN2
Centrin-2

1

2

High-throughput

0.407

High

58802

PRS4
26S proteasome regulatory subunit 4

1

16

High-throughput

0.407

High

58805

TOP2B
DNA topoisomerase 2-beta

1

1

High-throughput

0.407

High

58807

FOXM1
Forkhead box protein M1

1

1

High-throughput

0.407

High

58811

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

8

High-throughput

0.407

High

58813

ORC1
Origin recognition complex subunit 1

1

3

High-throughput

0.407

High

58817

BOP1
Ribosome biogenesis protein BOP1

1

3

High-throughput

0.407

High

58818

MAP7
Ensconsin

1

4

High-throughput

0.407

High

58820

TTLL4
Tubulin monoglutamylase TTLL4

1

1

High-throughput

0.407

High

58821

BMS1
Ribosome biogenesis protein BMS1 homolog

1

1

High-throughput

0.407

High

58829

TIGD5
Tigger transposable element-derived protein 5

1

2

High-throughput

0.407

High

58830

ZRAB3
DNA annealing helicase and endonuclease ZRANB3

1

5

High-throughput

0.407

High

58837

RL7L
Ribosomal protein uL30-like

1

2

High-throughput

0.407

High

58839

ADNP2
Activity-dependent neuroprotector homeobox protein 2

1

6

High-throughput

0.407

High

58843

LTMD1
LETM1 domain-containing protein 1

1

1

High-throughput

0.407

High

58844

SAMD1
Sterile alpha motif domain-containing protein 1

1

3

High-throughput

0.407

High

58845

SRCAP
Helicase SRCAP

1

4

High-throughput

0.407

High

58846

FA43B
Protein FAM43B

1

1

High-throughput

0.407

High

58849

MAVS
Mitochondrial antiviral-signaling protein

1

6

High-throughput

0.407

High

58852

IQGA3
Ras GTPase-activating-like protein IQGAP3

1

4

High-throughput

0.407

High

58859

MGAP
MAX gene-associated protein

1

1

High-throughput

0.407

High

58861

MIRO1
Mitochondrial Rho GTPase 1

1

12

High-throughput

0.407

High

58864

CDK20
Cyclin-dependent kinase 20

1

6

High-throughput

0.407

High

58867

FA43A
Protein FAM43A

1

5

High-throughput

0.407

High

58868

STAG2
Cohesin subunit SA-2

1

1

High-throughput

0.407

High

58869

GTPB8
GTP-binding protein 8

1

1

High-throughput

0.407

High

58880

ALMS1
Centrosome-associated protein ALMS1

1

2

High-throughput

0.407

High

58881

RBCC1
RB1-inducible coiled-coil protein 1

1

3

High-throughput

0.407

High

58895

ZBTB9
Zinc finger and BTB domain-containing protein 9

1

2

High-throughput

0.407

High

58896

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

1

High-throughput

0.407

High

58898

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

1

High-throughput

0.407

High

58904

LLR1
Leucine-rich repeat protein 1

1

4

High-throughput

0.407

High

58906

NSUN5
28S rRNA

1

1

High-throughput

0.407

High

58920

ZN747
Zinc finger protein 747

1

1

High-throughput

0.407

High

58924

PCGF6
Polycomb group RING finger protein 6

1

1

High-throughput

0.407

High

58926

S17A9
Voltage-gated purine nucleotide uniporter SLC17A9

1

3

High-throughput

0.407

High

58928

SETD5
Histone-lysine N-methyltransferase SETD5

1

3

High-throughput

0.407

High

58930

TSYL1
Testis-specific Y-encoded-like protein 1

1

2

High-throughput

0.407

High

58934

NSUN3
tRNA

1

1

High-throughput

0.407

High

58936

WDR76
WD repeat-containing protein 76

1

4

High-throughput

0.407

High

58938

RPF1
Ribosome production factor 1

1

1

High-throughput

0.407

High

58939

PKHA5
Pleckstrin homology domain-containing family A member 5

1

6

High-throughput

0.407

High

58940

MAGF1
Melanoma-associated antigen F1

1

4

High-throughput

0.407

High

58945

ASH1L
Histone-lysine N-methyltransferase ASH1L

1

2

High-throughput

0.407

High

58948

DCA13
DDB1- and CUL4-associated factor 13

1

5

High-throughput

0.407

High

58953

SMAL1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1

1

5

High-throughput

0.407

High

58956

H2AW
Core histone macro-H2A.2

1

3

High-throughput

0.407

High

58964

TSYL4
Testis-specific Y-encoded-like protein 4

1

2

High-throughput

0.407

High

58966

TSR3
18S rRNA aminocarboxypropyltransferase

1

1

High-throughput

0.407

High

58970

ABT1
Activator of basal transcription 1

1

1

High-throughput

0.407

High

58974

HS3S2
Heparan sulfate glucosamine 3-O-sulfotransferase 2

1

1

High-throughput

0.407

High

58975

HBS1L
HBS1-like protein

1

2

High-throughput

0.407

High

58978

HS3SA
Heparan sulfate glucosamine 3-O-sulfotransferase 3A1

1

1

High-throughput

0.407

High

50784

CA226
Uncharacterized protein C1orf226

1

0

High-throughput

0.232

Low

58754

SFI1
Protein SFI1 homolog

1

0

High-throughput

0.232

Low

58756

VMA5A
von Willebrand factor A domain-containing protein 5A

1

0

High-throughput

0.232

Low

58762

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

High-throughput

0.232

Low

58765

NDUB5
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial

1

0

High-throughput

0.232

Low

58771

B4GT4
Beta-1,4-galactosyltransferase 4

1

0

High-throughput

0.232

Low

58772

PEX10
Peroxisome biogenesis factor 10

1

0

High-throughput

0.232

Low

58774

NPHP4
Nephrocystin-4

1

0

High-throughput

0.232

Low

58780

MPC2
Mitochondrial pyruvate carrier 2

1

0

High-throughput

0.232

Low

58782

RPP29
Ribonuclease P protein subunit p29

1

0

High-throughput

0.232

Low

58787

ZN865
Zinc finger protein 865

1

0

High-throughput

0.232

Low

58791

XRCC1
DNA repair protein XRCC1

1

0

High-throughput

0.232

Low

58795

PRI1
DNA primase small subunit

1

0

High-throughput

0.232

Low

58796

PRI2
DNA primase large subunit

1

0

High-throughput

0.232

Low

58798

DNLI3
DNA ligase 3

1

0

High-throughput

0.232

Low

58803

LSM11
U7 snRNA-associated Sm-like protein LSm11

1

0

High-throughput

0.232

Low

58804

PYRD
Dihydroorotate dehydrogenase

1

0

High-throughput

0.232

Low

58816

NCOA4
Nuclear receptor coactivator 4

1

0

High-throughput

0.232

Low

58822

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.232

Low

58825

INF2
Inverted formin-2

1

0

High-throughput

0.232

Low

58828

RM51
Large ribosomal subunit protein mL51

1

0

High-throughput

0.232

Low

58831

CEP78
Centrosomal protein of 78 kDa

1

0

High-throughput

0.232

Low

58832

ATAT
Alpha-tubulin N-acetyltransferase 1

1

0

High-throughput

0.232

Low

58833

RM02
Large ribosomal subunit protein uL2m

1

0

High-throughput

0.232

Low

58835

ICE2
Little elongation complex subunit 2

1

0

High-throughput

0.232

Low

58836

Z518A
Zinc finger protein 518A

1

0

High-throughput

0.232

Low

58840

ALKB2
DNA oxidative demethylase ALKBH2

1

0

High-throughput

0.232

Low

58841

M18BP
Mis18-binding protein 1

1

0

High-throughput

0.232

Low

58847

MCM10
Protein MCM10 homolog

1

0

High-throughput

0.232

Low

58854

KMT5C
Histone-lysine N-methyltransferase KMT5C

1

0

High-throughput

0.232

Low

58858

CEP97
Centrosomal protein of 97 kDa

1

0

High-throughput

0.232

Low

58860

SKA3
Spindle and kinetochore-associated protein 3

1

0

High-throughput

0.232

Low

58862

T183A
Transmembrane protein 183A

1

0

High-throughput

0.232

Low

58863

ZC3H3
Zinc finger CCCH domain-containing protein 3

1

0

High-throughput

0.232

Low

58866

PUSL1
tRNA pseudouridine synthase-like 1

1

0

High-throughput

0.232

Low

58873

ANR29
Ankyrin repeat domain-containing protein 29

1

0

High-throughput

0.232

Low

58874

MACA2
Putative tyrosine carboxypeptidase MATCAP2

1

0

High-throughput

0.232

Low

58878

NEIL3
Endonuclease 8-like 3

1

0

High-throughput

0.232

Low

58886

F216A
Protein FAM216A

1

0

High-throughput

0.232

Low

58887

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.232

Low

58888

DCAKD
Dephospho-CoA kinase domain-containing protein

1

0

High-throughput

0.232

Low

58889

SKA2
Spindle and kinetochore-associated protein 2

1

0

High-throughput

0.232

Low

58890

ZN592
Zinc finger protein 592

1

0

High-throughput

0.232

Low

58892

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

0

High-throughput

0.232

Low

58893

ZN622
Cytoplasmic 60S subunit biogenesis factor ZNF622

1

0

High-throughput

0.232

Low

58894

SKA1
SKA complex subunit 1

1

0

High-throughput

0.232

Low

58897

THA11
THAP domain-containing protein 11

1

0

High-throughput

0.232

Low

58901

SENP5
Sentrin-specific protease 5

1

0

High-throughput

0.232

Low

58908

PUS7
Pseudouridylate synthase 7 homolog

1

0

High-throughput

0.232

Low

58909

CRML
Protein cramped-like

1

0

High-throughput

0.232

Low

58911

CTIP
DNA endonuclease RBBP8

1

0

High-throughput

0.232

Low

58915

CMS1
Protein CMSS1

1

0

High-throughput

0.232

Low

58916

SLX1
Structure-specific endonuclease subunit SLX1

1

0

High-throughput

0.232

Low

58918

MTG1
Mitochondrial ribosome-associated GTPase 1

1

0

High-throughput

0.232

Low

58919

CABL2
CDK5 and ABL1 enzyme substrate 2

1

0

High-throughput

0.232

Low

58923

RM20
Large ribosomal subunit protein bL20m

1

0

High-throughput

0.232

Low

58929

COA1
Cytochrome c oxidase assembly factor 1 homolog

1

0

High-throughput

0.232

Low

58932

DHX35
Probable ATP-dependent RNA helicase DHX35

1

0

High-throughput

0.232

Low

58933

PIF1
ATP-dependent DNA helicase PIF1

1

0

High-throughput

0.232

Low

58941

ZDBF2
DBF4-type zinc finger-containing protein 2

1

0

High-throughput

0.232

Low

58942

PLPL8
Calcium-independent phospholipase A2-gamma

1

0

High-throughput

0.232

Low

58946

ABCBA
ATP-binding cassette sub-family B member 10, mitochondrial

1

0

High-throughput

0.232

Low

58950

BCD1
Box C/D snoRNA protein 1

1

0

High-throughput

0.232

Low

58951

GTSE1
G2 and S phase-expressed protein 1

1

0

High-throughput

0.232

Low

58954

RM35
Large ribosomal subunit protein bL35m

1

0

High-throughput

0.232

Low

58955

RM36
Large ribosomal subunit protein bL36m

1

0

High-throughput

0.232

Low

58957

RM27
Large ribosomal subunit protein bL27m

1

0

High-throughput

0.232

Low

58958

SPAT7
Spermatogenesis-associated protein 7

1

0

High-throughput

0.232

Low

58963

MRM2
rRNA methyltransferase 2, mitochondrial

1

0

High-throughput

0.232

Low

58967

TASOR
Protein TASOR

1

0

High-throughput

0.232

Low

58973

PRLD1
PRELI domain-containing protein 1, mitochondrial

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025