HitPredict

Interactor 1: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Interactor 2: TBL3 (Q12788)
Transducin beta-like protein 3 (WD repeat-containing protein SAZD)
Gene: TBL3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 441 Hs			1 808
+	Mm
		1207948 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		TBL3_MOUSE (1-791): 0: 607: 89.63
+	Hs
		1016312 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		TBL3_HUMAN (1-808): 0: 635: 100.00
+	Mm
		291414 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		WDR1_MOUSE (385-772): 4.23e-42: 164: 14.61
+	Hs
		268105 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		PWP2_HUMAN (3-331): 2.47e-29: 127: 15.79
+	Hs
		268327 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		FBW1B_HUMAN (334-646): 6.06e-24: 108: 24.46
+	Hs
		268339 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		FBW1A_HUMAN (334-642): 7.67e-24: 108: 26.17
+	Hs
		1240442 POC1A_HUMAN (177-440): 1.72e-50: 177: 14.29		POC1B_HUMAN (417-750): 9.47e-61: 215: 20.29
+	Mm
		1206544 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		WDR3_MOUSE (2-94): 1.77e-16: 86.4: 10.64
+	Hs
		268334 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		WDR3_HUMAN (2-94): 8.52e-16: 84.1: 10.64
+	Mm
		1207284 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		PWP2_MOUSE (8-221): 3.13e-15: 82.2: 9.88
+	Dm
		1358859 FBXW7_DROME (224-441): 2.22e-25: 111: 15.53		WDS_DROME (2-278): 4.39e-71: 239: 14.79
+	Hs
		903418 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		WDR5_HUMAN (458-757): 3.76e-66: 225: 20.93
+	Dm
		1358845 WDS_DROME (267-440): 1.02e-23: 103: 15.34		WDS_DROME (2-278): 4.39e-71: 239: 14.79
+	Hs
		903428 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		WDR5_HUMAN (458-757): 3.76e-66: 225: 20.93
+	Hs
		903349 WDR5B_HUMAN (279-439): 2.9e-21: 96.1: 12.27		WDR5_HUMAN (458-757): 3.76e-66: 225: 20.93
+	Sc
		630844 NLE1_YEAST (4-263): 1.23e-51: 183: 14.05		NLE1_YEAST (561-752): 6.71e-34: 138: 13.78
+	Hs
		903551 NLE1_HUMAN (4-124): 2.95e-18: 88.8: 9.09		WDR5_HUMAN (458-757): 3.76e-66: 225: 20.93
+	Hs
		254111 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		WDR1_HUMAN (474-761): 5.72e-34: 140: 12.08
+	Hs
		1288390 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		WDR3_HUMAN (2-94): 8.52e-16: 84.1: 10.64