HitPredict

Interactor 1: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Interactor 2: PKP2 (Q99959)
Plakophilin-2
Gene: PKP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 441 Hs			1 881
+	Mm
		677651 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		CTND1_MOUSE (37-881): 1.84e-152: 474: 20.62
+	Mm
		1148450 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		PKP4_MOUSE (27-880): 3.88e-145: 461: 22.34
+	Mm
		970156 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		CTNB1_MOUSE (234-851): 2.32e-137: 429: 14.99
+	Hs
		268348 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		PKP3_HUMAN (29-870): 8.19e-134: 421: 23.03
+	Hs
		267873 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		PLAK_HUMAN (224-861): 1.84e-128: 405: 15.22
+	Hs
		245567 TBL1X_HUMAN (13-441): 1.12e-73: 243: 11.39		CTNB1_HUMAN (234-851): 2.18e-137: 429: 14.99
+	Mm
		192633 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		IMA3_MOUSE (284-809): 4.68e-109: 347: 12.29
+	Hs
		717329 TBL1R_HUMAN (4-335): 2.6e-56: 195: 11.40		CTNB1_HUMAN (234-851): 2.18e-137: 429: 14.99
+	Mm
		192641 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		IMA7_MOUSE (277-860): 5.26e-102: 329: 11.17
+	Hs
		239187 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		CTND1_HUMAN (37-881): 7.13e-149: 465: 20.87
+	Hs
		717264 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		CTNB1_HUMAN (234-851): 2.18e-137: 429: 14.99
+	Hs
		239105 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		CTND1_HUMAN (37-881): 7.13e-149: 465: 20.87
+	Hs
		1281508 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		PKP3_HUMAN (29-870): 8.19e-134: 421: 23.03
+	Hs
		542400 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		PLAK_HUMAN (224-861): 1.84e-128: 405: 15.22
+	Hs
		1045991 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		PKP1_HUMAN (107-879): 1.85e-125: 397: 22.99
+	Hs
		542260 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		PLAK_HUMAN (224-861): 1.84e-128: 405: 15.22
+	Dm
		578699 Q9VAK0_DROME (85-332): 6.08e-14: 75.5: 18.01		ARM_DROME (204-861): 2.72e-121: 389: 14.68
+	Hs
		131484 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		IMA4_HUMAN (281-809): 3.16e-106: 339: 12.78
+	Hs
		131487 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		IMA4_HUMAN (281-809): 3.16e-106: 339: 12.78
+	Hs
		238721 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		IMA7_HUMAN (277-860): 1.31e-101: 328: 11.34