HitPredict - High confidence protein-protein interactions

Interactor 1: BAF (O75531)
Barrier-to-autointegration factor (Breakpoint cluster region protein 1) [Cleaved into: Barrier-to-autointegration factor, N-terminally processed]
Gene: BANF1

Interactor 2: BAF (O75531)
Barrier-to-autointegration factor (Breakpoint cluster region protein 1) [Cleaved into: Barrier-to-autointegration factor, N-terminally processed]
Gene: BANF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.848

Property	Details
Experiments	10924106, 19759913, 16155580
Identification Methods	x-ray crystallography, affinity chromatography technology, molecular sieving, cosedimentation in solution
Interaction Type	association, physical association, direct interaction

Property	Details
Interacting Pfam domains	BAF~BAF
Common GO terms	GO:0000785 - chromatin GO:0000793 - condensed chromosome GO:0003677 - DNA binding GO:0003690 - double-stranded DNA binding GO:0005634 - nucleus and 16 others more... GO:0005635 - nuclear envelope GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006325 - chromatin organization GO:0006979 - response to oxidative stress GO:0007084 - mitotic nuclear membrane reassembly GO:0009615 - response to virus GO:0010836 - negative regulation of protein ADP-ribosylation GO:0015074 - DNA integration GO:0032480 - negative regulation of type I interferon production GO:0042803 - protein homodimerization activity GO:0045071 - negative regulation of viral genome replication GO:0045824 - negative regulation of innate immune response GO:0051276 - chromosome organization GO:0160049 - negative regulation of cGAS/STING signaling pathway
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	89
Hs

1	89

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024