HitPredict

Interactor 1: DAB1 (O75553)
Disabled homolog 1
Gene: DAB1

Interactor 2: LRP2 (P98164)
Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin)
Gene: LRP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.561

Property	Details
Experiments	10827173, 12508107
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 588 Hs			1 4655
+	Hs
		957621 ANS1B_HUMAN (9-229): 2.08e-44: 171: 17.70		LRP2_HUMAN (1-4655): 0: 3803: 100.00
+	Mm
		57553 DAB1_MOUSE (1-588): 3.86e-74: 249: 91.50		LRP2_MOUSE (22-4655): 0: 3723: 76.66
+	Hs
		957612 ARH_HUMAN (1-243): 1.04e-46: 168: 19.69		LRP2_HUMAN (1-4655): 0: 3803: 100.00
+	Hs
		957165 DAB2_HUMAN (8-587): 2.74e-41: 161: 23.98		LRP2_HUMAN (1-4655): 0: 3803: 100.00
+	Rn
		292326 DAB2_RAT (8-587): 1.42e-43: 168: 22.92		LRP2_RAT (1-4655): 0: 3738: 76.27
+	Mm
		57554 DAB2_MOUSE (8-587): 1.14e-43: 168: 23.51		LRP2_MOUSE (22-4655): 0: 3723: 76.66
+	Hs
		269114 DAB1_HUMAN (1-588): 2.31e-74: 250: 100.00		LDLR_HUMAN (927-1187): 1.96e-15: 86: 17.65
+	Mm
		729617 DAB1_MOUSE (1-588): 3.86e-74: 249: 91.50		LDLR_MOUSE (2609-2857): 2.23e-14: 82.6: 18.61
+	Hs
		269145 DAB1_HUMAN (1-588): 2.31e-74: 250: 100.00		LRP8_HUMAN (3464-3669): 8.96e-14: 80.7: 21.92
+	Mm
		956234 DAB1_MOUSE (1-588): 3.86e-74: 249: 91.50		LRP8_MOUSE (2623-2869): 2.33e-11: 72.6: 16.36
+	Mm
		69879 DAB1_MOUSE (1-588): 3.86e-74: 249: 91.50		B1AXJ3_MOUSE (3424-3628): 4.43e-11: 71.8: 12.50
+	Hs
		269133 DAB1_HUMAN (1-588): 2.31e-74: 250: 100.00		VLDLR_HUMAN (923-1143): 3.08e-10: 69.1: 15.11
+	Mm
		956222 DAB1_MOUSE (1-588): 3.86e-74: 249: 91.50		VLDLR_MOUSE (923-1146): 2.25e-10: 69.5: 15.35
+	Hs
		269141 DAB1_HUMAN (1-588): 2.31e-74: 250: 100.00		LRP1_HUMAN (1102-1387): 4.45e-09: 65.6: 13.59
+	Mm
		956233 DAB1_MOUSE (1-588): 3.86e-74: 249: 91.50		LRP1_MOUSE (3672-3974): 3.08e-09: 66: 10.16
+	Hs
		992719 GULP1_HUMAN (17-293): 2.72e-60: 204: 21.43		LRP1_HUMAN (1102-1387): 4.45e-09: 65.6: 13.59
+	Hs
		351073 ARH_HUMAN (1-243): 1.04e-46: 168: 19.69		LDLR_HUMAN (927-1187): 1.96e-15: 86: 17.65
+	Hs
		351065 DAB2_HUMAN (8-587): 2.74e-41: 161: 23.98		LDLR_HUMAN (927-1187): 1.96e-15: 86: 17.65
+	Hs
		992682 ANS1B_HUMAN (9-229): 2.08e-44: 171: 17.70		LRP1_HUMAN (1102-1387): 4.45e-09: 65.6: 13.59
+	Hs
		270287 DAB2_HUMAN (8-587): 2.74e-41: 161: 23.98		LRP6_HUMAN (3113-3241): 3.94e-09: 65.6: 16.30