Interactor 1: IGSF3 (O75054)
Immunoglobulin superfamily member 3 (IgSF3) (Glu-Trp-Ile EWI motif-containing protein 3) (EWI-3)
Gene: IGSF3

Interactor 2: LDLR (P01130)
Low-density lipoprotein receptor (LDL receptor)
Gene: LDLR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 39499777
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FXa_inhibition~V-set, Ldl_recept_a~V-set, Ldl_recept_b~V-set
Common GO terms GO:0009986 - cell surface
GO:0016020 - membrane
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1194
Hs

1 860
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 11Aug2025