Interactor 1: LRP6 (O75581)
Low-density lipoprotein receptor-related protein 6 (LRP-6)
Gene: LRP6

Interactor 2: GSK3A (P49840)
Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)
Gene: GSK3A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 0.60 0.649

The method score is based on:

Property Details
Experiments 16365045, 30824926
Identification Methods two hybrid, pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005102 - signaling receptor binding
GO:0016055 - Wnt signaling pathway
GO:0043025 - neuronal cell body
GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1613
Hs

1 483
+ Hs
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024