HitPredict

Interactor 1: LRP6 (O75581)
Low-density lipoprotein receptor-related protein 6 (LRP-6)
Gene: LRP6

Interactor 2: WNT3A (P56704)
Protein Wnt-3a
Gene: WNT3A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 0.60 0.689

The method score is based on:

Property Details
Experiments 33961781, 19910923, 21944579, 22726442
Identification Methods affinity chromatography technology, bio-layer interferometry, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005102 - signaling receptor binding
GO:0005109 - frizzled binding
GO:0005576 - extracellular region
GO:0005886 - plasma membrane
GO:0009986 - cell surface
and 6 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 1613
Hs

1 352
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024