HitPredict

Interactor 1: COBL (O75128)
Protein cordon-bleu
Gene: COBL

Interactor 2: ACTC (P68032)
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Gene: ACTC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~WH2
Common GO terms	GO:0005884 - actin filament GO:0016020 - membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1261 Hs			1 377
+	Hs
		271143 COBL_HUMAN (1-1261): 0: 1793: 100.00		ACTB_HUMAN (4-377): 0: 598: 94.12
+	Hs
		271150 COBL_HUMAN (1-1261): 0: 1793: 100.00		ACTG_HUMAN (4-377): 0: 598: 94.39
+	Hs
		995630 COBL1_HUMAN (1-876): 0: 968: 24.84		ACTC_HUMAN (1-377): 0: 599: 100.00
+	Hs
		952873 COBL1_HUMAN (1-876): 0: 968: 24.84		ACTB_HUMAN (4-377): 0: 598: 94.12
+	Hs
		993206 COBL1_HUMAN (1-876): 0: 968: 24.84		ACTG_HUMAN (4-377): 0: 598: 94.39