Protein: COBL1
Cordon-bleu protein-like 1

Gene: COBL1, COBLL1
Organism: Homo sapiens
Interactions: 59
UniProt ID: Q53SF7

Gene Ontology (top 5):
GO:0003785 - actin monomer binding
GO:0045296 - cadherin binding
GO:0070062 - extracellular exosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1200469

PACN3
Protein kinase C and casein kinase substrate in neurons protein 3

4

15

High-throughput

0.699

High

1200471

PACN2
Protein kinase C and casein kinase substrate in neurons protein 2

4

13

High-throughput

0.699

High

1200466

PACN1
Protein kinase C and casein kinase substrate in neurons protein 1

5

13

High-throughput

0.655

High

729894

1433B
14-3-3 protein beta/alpha

3

20

High-throughput

0.650

High

966403

1433G
14-3-3 protein gamma

3

20

High-throughput

0.650

High

1049359

1433F
14-3-3 protein eta

3

20

High-throughput

0.650

High

971596

1433E
14-3-3 protein epsilon

2

3

High-throughput

0.611

High

990296

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.611

High

582827

EZRI
Ezrin

2

14

High-throughput

0.584

High

691069

1433T
14-3-3 protein theta

2

20

High-throughput

0.571

High

365760

KAD1
Adenylate kinase isoenzyme 1

1

1

High-throughput

0.536

High

461559

HS90A
Heat shock protein HSP 90-alpha

1

5

High-throughput

0.536

High

993206

ACTG
Actin, cytoplasmic 2

1

17

High-throughput

0.536

High

159678

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

11

High-throughput

0.489

High

1089697

ILF3
Interleukin enhancer-binding factor 3

1

11

High-throughput

0.489

High

1200462

DLG3
Disks large homolog 3

1

7

High-throughput

0.489

High

1200464

SORT
Sortilin

1

1

High-throughput

0.489

High

363379

EGFR
Epidermal growth factor receptor

1

19

High-throughput

0.479

High

440103

LCK
Tyrosine-protein kinase Lck

1

11

High-throughput

0.479

High

459617

PROF1
Profilin-1

1

5

High-throughput

0.479

High

463560

LYN
Tyrosine-protein kinase Lyn

1

11

High-throughput

0.479

High

556128

CADH1
Cadherin-1

1

3

High-throughput

0.479

High

715616

MARCS
Myristoylated alanine-rich C-kinase substrate

1

8

High-throughput

0.479

High

730635

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

767448

RADI
Radixin

1

12

High-throughput

0.479

High

896545

VASP
Vasodilator-stimulated phosphoprotein

1

3

High-throughput

0.479

High

952873

ACTB
Actin, cytoplasmic 1

1

17

High-throughput

0.479

High

955249

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

995630

ACTC
Actin, alpha cardiac muscle 1

1

13

High-throughput

0.479

High

998394

H31
Histone H3.1

1

17

High-throughput

0.479

High

1141647

EEA1
Early endosome antigen 1

1

11

High-throughput

0.479

High

1200463

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

9

High-throughput

0.457

High

1200456

PKHA7
Pleckstrin homology domain-containing family A member 7

1

12

High-throughput

0.445

High

934213

BI1
Bax inhibitor 1

1

2

High-throughput

0.439

High

229532

NRDC
Nardilysin

1

1

Small-scale

0.437

High

400937

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

6

High-throughput

0.437

High

541529

FGFR1
Fibroblast growth factor receptor 1

1

13

High-throughput

0.437

High

642912

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

4

High-throughput

0.437

High

1041101

CAV1
Caveolin-1

1

5

High-throughput

0.437

High

1059860

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

1

High-throughput

0.437

High

1068835

IFFO1
Non-homologous end joining factor IFFO1

1

8

High-throughput

0.437

High

1112527

CUL1
Cullin-1

1

10

Small-scale

0.437

High

1159676

OCLN
Occludin

1

2

High-throughput

0.437

High

1200454

A16L1
Autophagy-related protein 16-1

1

13

High-throughput

0.437

High

1200457

HMBX1
Homeobox-containing protein 1

1

16

High-throughput

0.437

High

1200459

TLK2
Serine/threonine-protein kinase tousled-like 2

1

4

High-throughput

0.437

High

1200460

AMOL1
Angiomotin-like protein 1

1

13

High-throughput

0.437

High

1200468

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.437

High

1200470

SCML1
Sex comb on midleg-like protein 1

1

1

High-throughput

0.437

High

703613

MK01
Mitogen-activated protein kinase 1

1

3

High-throughput

0.407

High

1200453

BTBD8
BTB/POZ domain-containing protein 8

1

9

High-throughput

0.407

High

341949

CEP43
Centrosomal protein 43

1

0

High-throughput

0.279

Low

1102987

CENPR
Centromere protein R

1

0

High-throughput

0.279

Low

1200455

P4R3A
Serine/threonine-protein phosphatase 4 regulatory subunit 3A

1

0

High-throughput

0.279

Low

49110

BLT3B
Bridge-like lipid transfer protein family member 3B

1

0

High-throughput

0.249

Low

1200461

DDHD1
Phospholipase DDHD1

1

0

High-throughput

0.249

Low

1200465

CDAC1
Cytidine and dCMP deaminase domain-containing protein 1

1

0

High-throughput

0.249

Low

1200467

F117A
Protein FAM117A

1

0

High-throughput

0.249

Low

1200458

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025