Interactor 1: DEPD5 (O75140)
GATOR1 complex protein DEPDC5 (DEP domain-containing protein 5)
Gene: DEPDC5
Interactor 2: NPRL2 (Q8WTW4)
GATOR1 complex protein NPRL2 (Gene 21 protein) (G21 protein) (Nitrogen permease regulator 2-like protein) (NPR2-like protein) (Tumor suppressor candidate 4)
Gene: NPRL2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.972 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | IML1~NPR2 |
| Common GO terms | GO:0005096 - GTPase activator activity GO:0005765 - lysosomal membrane GO:0010508 - positive regulation of autophagy GO:0034198 - cellular response to amino acid starvation GO:1904262 - negative regulation of TORC1 signaling and 1 others more... |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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| + | Sp |  |
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
