Interactor 1: U520 (O75643)
U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog) (U5 snRNP-specific 200 kDa protein) (U5-200KD)
Gene: SNRNP200

Interactor 2: SPF27 (O75934)
Pre-mRNA-splicing factor SPF27 (Breast carcinoma-amplified sequence 2) (DNA amplified in mammary carcinoma 1 protein) (Spliceosome-associated protein SPF 27)
Gene: BCAS2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 0.60 0.614

The method score is based on:

Property Details
Experiments 25849387, 33961781
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005681 - spliceosomal complex
GO:0071013 - catalytic step 2 spliceosome
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 2136
Hs

1 225
+ At
+ Sp
+ Hs
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024