HitPredict

Interactor 1: U520 (O75643)
U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog) (U5 snRNP-specific 200 kDa protein) (U5-200KD)
Gene: SNRNP200

Interactor 2: ISG15 (P05161)
Ubiquitin-like protein ISG15 (Interferon-induced 15 kDa protein) (Interferon-induced 17 kDa protein) (IP17) (Ubiquitin cross-reactive protein) (hUCRP)
Gene: ISG15

Species: Homo sapiens

Source: innatedb

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	33024031, 16009940
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 2136 Hs			1 165
+	At
		1092410 DEXHC_ARATH (2-2130): 0: 1646: 56.50		UBQ3_ARATH (3-157): 2.86e-64: 200: 33.55
+	At
		221257 DEXHD_ARATH (2-2130): 0: 1626: 55.06		UBQ3_ARATH (3-157): 2.86e-64: 200: 33.55
+	Hs
		476041 ASCC3_HUMAN (56-2134): 0: 1449: 38.34		UBC_HUMAN (3-157): 5.42e-62: 203: 32.26
+	At
		98670 F4K203_ARATH (27-2123): 0: 1423: 38.57		UBQ3_ARATH (3-157): 2.86e-64: 200: 33.55
+	Hs
		398032 ASCC3_HUMAN (56-2134): 0: 1449: 38.34		ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00
+	Mm
		93326 ASCC3_MOUSE (56-2136): 0: 1445: 38.09		UBC_MOUSE (2-110): 1.68e-33: 126: 28.44
+	Hs
		476139 DDX17_HUMAN (405-901): 6.31e-105: 356: 13.72		UBC_HUMAN (3-157): 5.42e-62: 203: 32.26
+	At
		1092478 HEN2_ARATH (1254-1759): 2.05e-94: 332: 20.18		UBQ3_ARATH (3-157): 2.86e-64: 200: 33.55
+	Hs
		398024 DDX42_HUMAN (231-900): 2.59e-103: 357: 13.42		ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00
+	Hs
		398056 DDX17_HUMAN (405-901): 6.31e-105: 356: 13.72		ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00
+	Hs
		1074461 SKI2_HUMAN (1292-1738): 8.82e-97: 344: 24.21		OASL_HUMAN (3-163): 2.74e-39: 140: 24.39
+	At
		1013123 DNJ21_ARATH (1819-2128): 1.93e-74: 265: 26.21		UBQ3_ARATH (3-157): 2.86e-64: 200: 33.55
+	Hs
		398082 DDX23_HUMAN (1241-1748): 1.71e-87: 307: 14.36		ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00
+	Hs
		224752 DHX16_HUMAN (1094-2008): 1.27e-67: 252: 11.11		UBC_HUMAN (3-157): 5.42e-62: 203: 32.26
+	Hs
		475760 DHX8_HUMAN (1313-1903): 1.71e-65: 247: 11.81		UBC_HUMAN (3-157): 5.42e-62: 203: 32.26
+	Pf
		1181541 Q8I416_PLAF7 (1303-1710): 2.05e-48: 193: 14.56		Q7KQK2_PLAF7 (3-157): 1.04e-64: 204: 31.61
+	Mm
		476954 Q921Y1_MOUSE (1094-2008): 4.57e-66: 247: 10.85		UBC_MOUSE (2-110): 1.68e-33: 126: 28.44