HitPredict

Interactor 1: U520 (O75643)
U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog) (U5 snRNP-specific 200 kDa protein) (U5-200KD)
Gene: SNRNP200

Interactor 2: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30472188, 38280479
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016020 - membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 2136 Hs			1 504
+	Hs
		125048 U520_HUMAN (1-2136): 0: 1844: 100.00		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		272296 U520_HUMAN (1-2136): 0: 1844: 100.00		WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61
+	Hs
		125576 ASCC3_HUMAN (56-2134): 0: 1449: 38.34		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		1232202 ASCC3_HUMAN (56-2134): 0: 1449: 38.34		WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83
+	Hs
		1232218 ASCC3_HUMAN (56-2134): 0: 1449: 38.34		HECW2_HUMAN (13-303): 1.56e-14: 79: 14.79
+	Hs
		125142 DDX5_HUMAN (1241-1718): 1.86e-108: 362: 12.47		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		125617 DDX17_HUMAN (405-901): 6.31e-105: 356: 13.72		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		125215 MTREX_HUMAN (1287-2037): 2.62e-101: 354: 18.12		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		125480 SKI2_HUMAN (1292-1738): 8.82e-97: 344: 24.21		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		571603 DDX5_HUMAN (1241-1718): 1.86e-108: 362: 12.47		SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05
+	Hs
		571348 DDX5_HUMAN (1241-1718): 1.86e-108: 362: 12.47		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		808816 DDX17_HUMAN (405-901): 6.31e-105: 356: 13.72		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Mm
		809069 DDX17_MOUSE (405-901): 7.77e-106: 356: 13.72		YAP1_MOUSE (35-504): 1.41e-115: 351: 91.70
+	Hs
		1271653 DDX17_HUMAN (405-901): 6.31e-105: 356: 13.72		WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83
+	Sc
		624167 DBP2_YEAST (347-898): 8.71e-101: 338: 13.47		TOM1_YEAST (261-504): 2.18e-46: 176: 11.34
+	Sc
		810906 MTR4_YEAST (1270-1848): 1.11e-94: 335: 19.41		TOM1_YEAST (261-504): 2.18e-46: 176: 11.34
+	Hs
		1271684 DDX17_HUMAN (405-901): 6.31e-105: 356: 13.72		WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61