Protein: ACT6
Actin, indirect flight muscle (EC 3.6.4.-) (Actin-88F)

Gene: ACT6, Act88F
Organism: Drosophila melanogaster
Interactions: 61
UniProt ID: P83967

Gene Ontology (top 5):
GO:0000281 - mitotic cytokinesis
GO:0005524 - ATP binding
GO:0005865 - striated muscle thin filament
GO:0015629 - actin cytoskeleton
GO:0016787 - hydrolase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

386976

ACT2
Actin-42A

3

19

High-throughput

0.839

High

432182

MYSA
Myosin heavy chain, muscle

3

13

High-throughput

0.797

High

387039

ACT4
Actin, larval muscle

2

19

High-throughput

0.767

High

534352

ACT5
Actin-87E

2

19

High-throughput

0.767

High

920976

ACT3
Actin-57B

2

19

High-throughput

0.767

High

1014432

ACT6
Actin, indirect flight muscle

2

19

High-throughput

0.767

High

1014455

Q9VPX6
Adenylyl cyclase-associated protein

2

20

High-throughput

0.686

High

1014456

WDR1
Actin-interacting protein 1

2

16

High-throughput

0.686

High

446275

MLC1
Myosin light chain alkali

2

3

High-throughput

0.659

High

482740

TPM2
Tropomyosin-2

2

15

High-throughput

0.659

High

852484

CADF
Cofilin/actin-depolymerizing factor homolog

1

20

High-throughput

0.656

High

1014460

Q9VWR1
IP04855p

1

20

High-throughput

0.656

High

56405

A1ZA72
Stretchin-Mlck, isoform V

1

12

High-throughput

0.618

High

1014439

Q7KNM2
Dorsal interacting protein 4

2

4

High-throughput

0.594

High

620765

TNNT
Troponin T, skeletal muscle

1

5

High-throughput

0.575

High

1014450

FLNA
Filamin-A

1

20

High-throughput

0.575

High

1014451

TWF
Twinfilin

1

20

High-throughput

0.575

High

1014465

CAPZA
F-actin-capping protein subunit alpha

1

9

High-throughput

0.575

High

460015

ALF
Fructose-bisphosphate aldolase

2

3

High-throughput

0.571

High

567554

GPDA
Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

2

2

High-throughput

0.571

High

614562

MLR
Myosin regulatory light chain 2

2

6

High-throughput

0.571

High

561567

SPTCA
Spectrin alpha chain

1

20

Small-scale

0.553

High

1014437

Q7K569
Glycerol-3-phosphate dehydrogenase

1

5

High-throughput

0.553

High

1014454

GRCR1
Glutaredoxin domain-containing cysteine-rich protein CG31559

2

6

High-throughput

0.542

High

1014467

GRCR2
Glutaredoxin domain-containing cysteine-rich protein CG12206

2

6

High-throughput

0.542

High

358474

ADH
Alcohol dehydrogenase

2

3

High-throughput

0.521

High

831769

GSTS1
Glutathione S-transferase S1

2

3

High-throughput

0.521

High

1014435

Q6IHY5
Cytochrome c oxidase subunit 7A-like 2, isoform A

2

1

High-throughput

0.521

High

1014453

Q9VIE8
Aconitate hydratase, mitochondrial

2

2

High-throughput

0.521

High

1014466

CISY
Probable citrate synthase, mitochondrial

2

1

High-throughput

0.521

High

1014438

Q7K860
FI07231p

1

3

High-throughput

0.514

High

1014441

Q8MYR8
RH74685p

1

4

High-throughput

0.514

High

1014463

Q9VZM9
RE59328p

1

15

High-throughput

0.514

High

682722

PROF
Profilin

1

18

High-throughput

0.492

High

1014433

FLII
Protein flightless-1

1

20

High-throughput

0.492

High

1014444

TITIN
Titin

1

15

High-throughput

0.492

High

1014440

LASP1
LIM and SH3 domain protein Lasp

1

20

Small-scale

0.479

High

1014445

ANLN
Anillin

1

10

Small-scale

0.479

High

1014457

PYRG
CTP synthase

1

2

High-throughput

0.479

High

875403

KARG
Arginine kinase 1

1

3

High-throughput

0.445

High

68708

A8JQV1
Uncharacterized protein, isoform C

1

13

High-throughput

0.437

High

669586

OSKA
Maternal effect protein oskar

1

4

Small-scale

0.437

High

1014442

Q8T0T2
GH09296p

1

5

Small-scale

0.437

High

1014462

PGPLE
Peptidoglycan-recognition protein LE

1

5

High-throughput

0.437

High

458089

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

1

High-throughput

0.407

High

928945

DOD
Putative peptidyl-prolyl cis-trans isomerase dodo

1

1

High-throughput

0.407

High

1014434

Q4V467
IP10845p

1

13

High-throughput

0.407

High

1014436

Q7JUS9
Phosphate carrier protein, mitochondrial

1

5

High-throughput

0.407

High

1014443

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

1

High-throughput

0.407

High

1014447

Q9VBF5
Fructose-bisphosphate aldolase

1

3

High-throughput

0.407

High

1014448

Q9VDF4
Cortactin, isoform A

1

20

High-throughput

0.407

High

1014449

Q9VEB1
Malate dehydrogenase, mitochondrial

1

2

High-throughput

0.407

High

1014452

Q9VGD9
GH04404p1

1

5

High-throughput

0.407

High

1014458

Q9VVT4
IP10578p

2

0

High-throughput

0.310

High

1014464

Q9W0B3
Vacuolar protein sorting-associated protein VTA1 homolog

2

0

High-throughput

0.310

High

772243

FTN
Flightin

2

0

High-throughput

0.298

High

1014459

NDUS4
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial

1

0

High-throughput

0.249

Low

701279

SUH
Suppressor of hairless protein

1

0

High-throughput

0.232

Low

1014446

Q9V9V7
LD23072p

1

0

High-throughput

0.232

Low

1014461

Q9VWY9
GH28353p

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025