Protein: ACTC
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]

Gene: ACTC, Actc1
Organism: Mus musculus
Interactions: 17
UniProt ID: P68033

Gene Ontology (top 5):
GO:0000146 - microfilament motor activity
GO:0005524 - ATP binding
GO:0005884 - actin filament
GO:0009410 - response to xenobiotic stimulus
GO:0010628 - positive regulation of gene expression

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

267094

MYPC3
Myosin-binding protein C, cardiac-type

1

7

Small-scale

0.590

High

995938

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

10

High-throughput

0.590

High

995936

EED
Polycomb protein EED

1

10

High-throughput

0.553

High

530781

TAU
Microtubule-associated protein tau

1

15

High-throughput

0.479

High

771456

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

5

High-throughput

0.479

High

995928

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

5

High-throughput

0.479

High

995932

RIGI
Antiviral innate immune response receptor RIG-I

1

4

High-throughput

0.479

High

995933

NEB2
Neurabin-2

1

13

High-throughput

0.479

High

778162

BTK
Tyrosine-protein kinase BTK

1

5

High-throughput

0.457

High

995930

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

7

High-throughput

0.445

High

947658

NPHP4
Nephrocystin-4

1

3

High-throughput

0.437

High

995929

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

4

High-throughput

0.437

High

995931

TFE3
Transcription factor E3

1

4

High-throughput

0.437

High

995934

SPOP
Speckle-type POZ protein

1

12

High-throughput

0.437

High

995935

DMRT2
Doublesex- and mab-3-related transcription factor 2

1

1

Small-scale

0.437

High

995937

RN138
E3 ubiquitin-protein ligase RNF138

1

17

Small-scale

0.437

High

995927

THIOM
Thioredoxin, mitochondrial

1

8

High-throughput

0.407

High


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Last updated: 11Aug2025