HitPredict

Interactor 1: U520 (O75643)
U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog) (U5 snRNP-specific 200 kDa protein) (U5-200KD)
Gene: SNRNP200

Interactor 2: RBM39 (Q14498)
RNA-binding protein 39 (CAPER alpha) (CAPERalpha) (Hepatocellular carcinoma protein 1) (RNA-binding motif protein 39) (RNA-binding region-containing protein 2) (Splicing factor HCC1)
Gene: RBM39

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	28302793, 35271311, 16051665
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 2136 Hs			1 530
+	Hs
		516589 ASCC3_HUMAN (56-2134): 0: 1449: 38.34		PABP1_HUMAN (41-426): 4.09e-61: 214: 19.08
+	Sp
		678721 BRR2_SCHPO (10-2129): 0: 1452: 48.16		PABP_SCHPO (40-471): 3.6e-56: 200: 13.61
+	Sc
		376698 BRR2_YEAST (4-2127): 0: 1258: 38.75		PABP_YEAST (40-441): 6.66e-53: 190: 12.17
+	Hs
		571452 DDX5_HUMAN (1241-1718): 1.86e-108: 362: 12.47		RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00
+	Hs
		1054414 DDX42_HUMAN (231-900): 2.59e-103: 357: 13.42		RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00
+	Hs
		1054481 DDX17_HUMAN (405-901): 6.31e-105: 356: 13.72		RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00
+	Hs
		786947 MTREX_HUMAN (1287-2037): 2.62e-101: 354: 18.12		RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00
+	Hs
		1054552 DDX23_HUMAN (1241-1748): 1.71e-87: 307: 14.36		RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00
+	Sp
		143392 PRP11_SCHPO (1203-1772): 1.04e-91: 324: 14.09		RSD1_SCHPO (18-521): 2.36e-85: 277: 31.38
+	Sp
		143069 YE02_SCHPO (1285-1736): 1.23e-86: 310: 21.71		YHKF_SCHPO (16-420): 1.18e-88: 282: 16.16
+	Hs
		1054310 DHX8_HUMAN (1313-1903): 1.71e-65: 247: 11.81		RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00
+	Hs
		1054476 PRP16_HUMAN (1317-1920): 4.33e-65: 246: 11.76		RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00
+	Hs
		1313211 DDX23_HUMAN (1241-1748): 1.71e-87: 307: 14.36		PUF60_HUMAN (141-513): 7.12e-66: 225: 19.41
+	Sc
		376837 MTR4_YEAST (1270-1848): 1.11e-94: 335: 19.41		PABP_YEAST (40-441): 6.66e-53: 190: 12.17
+	Sp
		143097 YE02_SCHPO (1285-1736): 1.23e-86: 310: 21.71		PABP_SCHPO (40-471): 3.6e-56: 200: 13.61
+	Hs
		1073596 DDX42_HUMAN (231-900): 2.59e-103: 357: 13.42		SF3B4_HUMAN (238-395): 5.66e-23: 103: 22.79
+	Hs
		1073611 DDX17_HUMAN (405-901): 6.31e-105: 356: 13.72		SF3B4_HUMAN (238-395): 5.66e-23: 103: 22.79
+	Hs
		161959 DDX5_HUMAN (1241-1718): 1.86e-108: 362: 12.47		HNRDL_HUMAN (144-309): 3.62e-15: 79.7: 31.93