Interactor 1: U520 (O75643)
U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog) (U5 snRNP-specific 200 kDa protein) (U5-200KD)
Gene: SNRNP200
Interactor 2: PRP8 (Q6P2Q9)
Pre-mRNA-processing-splicing factor 8 (220 kDa U5 snRNP-specific protein) (PRP8 homolog) (Splicing factor Prp8) (p220)
Gene: PRPF8
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.970 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27173435, 28515276, 34079125, 35271311, 16723661, 17317632, 31914407, 37071682, 23704370 |
| Identification Methods | affinity chromatography technology, proximity labelling technology, two hybrid, x-ray crystallography, cross-linking study, molecular sieving, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DEAD~PROCT, Helicase_C~PROCT, JAB~Sec63, PROCT~Sec63 |
| Common GO terms | GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005682 - U5 snRNP and 5 others more... |
| Homologous interactions | 9 |
Homologous interactions
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Last updated: 15 Jul 2024
