HitPredict

Interactor 1: KS6A4 (O75676)
Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 4) (Nuclear mitogen- and stress-activated protein kinase 2) (Ribosomal protein kinase B) (RSKB)
Gene: RPS6KA4

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045202 - synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 772 Hs			1 245
+	Hs
		272852 KS6A4_HUMAN (1-772): 0: 787: 100.00		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		270395 KS6A5_HUMAN (2-772): 0: 765: 59.38		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		646741 KS6A3_HUMAN (1-740): 0: 703: 41.21		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		646913 KS6A1_HUMAN (3-739): 0: 701: 40.79		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		272860 KS6A4_HUMAN (1-772): 0: 787: 100.00		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		683216 KS6A3_HUMAN (1-740): 0: 703: 41.21		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		272857 KS6A4_HUMAN (1-772): 0: 787: 100.00		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		683368 KS6A1_HUMAN (3-739): 0: 701: 40.79		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Rn
		716565 KS6A1_RAT (3-739): 0: 703: 41.06		1433B_RAT (1-242): 9.21e-126: 358: 81.41
+	Hs
		850642 KS6A3_HUMAN (1-740): 0: 703: 41.21		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		850630 KS6A3_HUMAN (1-740): 0: 703: 41.21		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		982035 KS6A1_HUMAN (3-739): 0: 701: 40.79		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		904590 KS6A1_HUMAN (3-739): 0: 701: 40.79		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		681770 AKT1_HUMAN (402-742): 4.52e-120: 371: 25.42		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		681776 AKT1_HUMAN (402-742): 4.52e-120: 371: 25.42		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		647354 KS6B2_HUMAN (411-771): 2.6e-113: 354: 23.82		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		568616 KAPCA_HUMAN (398-704): 1.94e-108: 336: 26.88		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		681682 AKT1_HUMAN (402-742): 4.52e-120: 371: 25.42		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Hs
		681766 AKT1_HUMAN (402-742): 4.52e-120: 371: 25.42		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		982585 KS6B2_HUMAN (411-771): 2.6e-113: 354: 23.82		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43