Protein: SPP1
COMPASS component SPP1 (Complex proteins associated with SET1 protein SPP1) (Set1C component SPP1) (Suppressor of PRP protein 1)

Gene: SPP1
Organism: Saccharomyces cerevisiae S288C
Interactions: 53
UniProt ID: Q03012

Gene Ontology (top 5):
GO:0000781 - chromosome, telomeric region
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006355 - regulation of DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

963675

H3
Histone H3

6

20

Small-scale

0.936

High

805573

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

18

17

Small-scale

0.767

High

845936

BRE2
COMPASS component BRE2

13

5

Small-scale

0.759

High

793868

SWD3
COMPASS component SWD3

9

7

Small-scale

0.752

High

813668

SWD1
COMPASS component SWD1

7

10

Small-scale

0.747

High

781155

SWD2
COMPASS component SWD2

7

8

Small-scale

0.746

High

639511

RE107
Recombination protein 107

4

0

Small-scale

0.680

High

1040461

SDC1
COMPASS component SDC1

4

0

Small-scale

0.664

High

381227

H2B1
Histone H2B.1

1

20

Small-scale

0.647

High

798407

SHG1
COMPASS component SHG1

3

0

Small-scale

0.634

High

777101

BDF1
Bromodomain-containing factor 1

1

20

High-throughput

0.621

High

924835

NOP15
Ribosome biogenesis protein 15

1

4

High-throughput

0.618

High

1040460

SPP1
COMPASS component SPP1

1

6

Small-scale

0.618

High

1040462

SCC2
Sister chromatid cohesion protein 2

2

1

High-throughput

0.586

High

524939

HSP71
Heat shock protein SSA1

2

5

High-throughput

0.571

High

745668

ORC2
Origin recognition complex subunit 2

1

1

Small-scale

0.552

High

527509

HSP72
Heat shock protein SSA2

2

5

High-throughput

0.552

High

758048

MTR2
mRNA transport regulator MTR2

1

0

High-throughput

0.518

High

437952

KAPC
cAMP-dependent protein kinase type 3

1

1

High-throughput

0.501

High

656847

KC12
Casein kinase I homolog 2

1

3

High-throughput

0.501

High

752649

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.489

High

829789

MAD1
Spindle assembly checkpoint component MAD1

1

5

High-throughput

0.481

High

402099

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

2

Small-scale

0.479

High

707984

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

749715

TYE7
Transcription factor TYE7

1

0

High-throughput

0.460

High

866060

NNF1
Kinetochore-associated protein NNF1

1

0

High-throughput

0.460

High

1040464

ARR1
Arsenical-resistance protein ARR1

1

0

High-throughput

0.460

High

812602

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

932316

ORC3
Origin recognition complex subunit 3

1

0

Small-scale

0.458

High

1040463

VPS20
Vacuolar protein sorting-associated protein 20

1

0

High-throughput

0.458

High

649662

KCC2
Calcium/calmodulin-dependent protein kinase II

1

3

High-throughput

0.457

High

546017

SSB1
Ribosome-associated molecular chaperone SSB1

1

6

High-throughput

0.445

High

676286

MAS5
Mitochondrial protein import protein MAS5

1

3

High-throughput

0.445

High

742251

HSP7F
Heat shock protein homolog SSE1

1

7

High-throughput

0.445

High

819604

SSB2
Ribosome-associated molecular chaperone SSB2

1

6

High-throughput

0.445

High

1040466

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

1

High-throughput

0.445

High

809223

END3
Actin cytoskeleton-regulatory complex protein END3

1

1

High-throughput

0.439

High

1040467

SLK19
Kinetochore protein SLK19

1

5

High-throughput

0.439

High

764145

SPT21
Protein SPT21

1

0

High-throughput

0.438

High

830019

LYS14
Lysine biosynthesis regulatory protein LYS14

1

0

High-throughput

0.438

High

739741

SPT16
FACT complex subunit SPT16

1

1

High-throughput

0.437

High

1038816

LGE1
Transcriptional regulatory protein LGE1

1

0

High-throughput

0.426

High

810750

TCPB
T-complex protein 1 subunit beta

1

1

High-throughput

0.407

High

811022

TCPD
T-complex protein 1 subunit delta

1

1

High-throughput

0.407

High

803744

YHI9
Uncharacterized isomerase YHI9

1

0

High-throughput

0.269

Low

1040468

POM33
Pore membrane protein of 33 kDa

1

0

High-throughput

0.269

Low

735662

SMY1
Kinesin-related protein SMY1

1

0

High-throughput

0.251

Low

748233

VAM7
Vacuolar morphogenesis protein 7

1

0

High-throughput

0.251

Low

796354

FL2D
Protein MUM2

1

0

High-throughput

0.251

Low

776334

MRP8
Uncharacterized protein MRP8

1

0

High-throughput

0.249

Low

1040465

GPI11
Glycosylphosphatidylinositol anchor biosynthesis protein 11

1

0

High-throughput

0.249

Low

844432

TCPH
T-complex protein 1 subunit eta

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025