Interactor 1: ADAP1 (O75689)
Arf-GAP with dual PH domain-containing protein 1 (Centaurin-alpha-1) (Cnt-a1) (Putative MAPK-activating protein PM25)
Gene: ADAP1

Interactor 2: KPCE (Q02156)
Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)
Gene: PRKCE

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.59 1.00 0.771

The method score is based on:

Property Details
Experiments 12893243
Identification Methods enzymatic study, pull down, protein kinase assay
Interaction Type direct interaction, physical association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~PH, PH~Pkinase
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0043231 - intracellular membrane-bounded organelle
and 1 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 374
Hs

1 737
+ Mm
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Mm
+ Rn
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs

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Last updated: 15 Jul 2024