HitPredict

Interactor 1: SIN3B (O75182)
Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b)
Gene: SIN3B

Interactor 2: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	33640491, 16469706
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 1 others more... GO:0005737 - cytoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1162 Hs			1 920
+	Hs
		274275 SIN3B_HUMAN (1-1162): 0: 1451: 100.00		ESR1_HUMAN (378-904): 7.63e-136: 420: 22.20
+	Hs
		274362 SIN3B_HUMAN (1-1162): 0: 1451: 100.00		ESR2_HUMAN (435-912): 2.49e-116: 367: 21.51
+	Hs
		520312 SIN3A_HUMAN (78-366): 2.04e-15: 83.8: 15.60		ANDR_HUMAN (1-920): 0: 966: 100.00
+	Hs
		396768 SIN3A_HUMAN (78-366): 2.04e-15: 83.8: 15.60		ESR1_HUMAN (378-904): 7.63e-136: 420: 22.20
+	Hs
		848109 SIN3A_HUMAN (78-366): 2.04e-15: 83.8: 15.60		NR4A2_HUMAN (307-905): 2.76e-119: 377: 16.72
+	Hs
		1367085 SIN3A_HUMAN (78-366): 2.04e-15: 83.8: 15.60		ESR2_HUMAN (435-912): 2.49e-116: 367: 21.51