HitPredict

Interactor 1: WDHD1 (O75717)
WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA-binding protein 1) (And-1)
Gene: WDHD1

Interactor 2: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	26082189, 37827155, 24332808
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0006261 - DNA-templated DNA replication GO:0006281 - DNA repair
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1129 Hs			1 616
+	Hs
		650511 COPB2_HUMAN (1-990): 2.64e-112: 373: 11.12		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		651925 SNR40_HUMAN (3-212): 6.74e-47: 174: 18.10		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Sc
		607322 CTF4_YEAST (19-823): 2.81e-102: 346: 18.34		RFA1_YEAST (4-615): 0: 596: 31.69
+	Hs
		650759 COPA_HUMAN (6-210): 1.83e-22: 106: 10.38		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		652407 NLE1_HUMAN (410-722): 4.18e-18: 91: 9.79		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		651439 A16L1_HUMAN (125-279): 5.5e-16: 84.9: 16.03		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Mm
		1207646 A16L1_MOUSE (11-257): 2.22e-25: 114: 16.00		RFA1_MOUSE (1-614): 0: 745: 83.95
+	Hs
		652609 WDR3_HUMAN (490-870): 1.53e-12: 74.1: 9.18		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		650859 WDR5_HUMAN (559-722): 4.48e-09: 61.3: 13.74		RFA1_HUMAN (1-616): 0: 781: 100.00