HitPredict

Interactor 1: EIF3G (O75821)
Eukaryotic translation initiation factor 3 subunit G (eIF3g) (Eukaryotic translation initiation factor 3 RNA-binding subunit) (eIF-3 RNA-binding subunit) (Eukaryotic translation initiation factor 3 subunit 4) (eIF-3-delta) (eIF3 p42) (eIF3 p44)
Gene: EIF3G

Interactor 2: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29845934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	La~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 320 Hs			1 582
+	Hs
		1116304 PAP1L_HUMAN (230-319): 2.16e-24: 105: 26.67		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		1031352 PABP4_HUMAN (230-320): 6.63e-24: 104: 24.18		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		516541 PABP1_HUMAN (230-320): 3.49e-24: 104: 26.37		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Sc
		376921 EIF3G_YEAST (56-318): 1.08e-56: 186: 32.23		PABP_YEAST (9-243): 8.44e-33: 134: 13.47
+	At
		285476 PABP2_ARATH (211-320): 2.23e-24: 105: 20.00		LRP6B_ARATH (2-265): 6.42e-54: 194: 21.20
+	At
		790116 PABP2_ARATH (211-320): 2.23e-24: 105: 20.00		LRP6C_ARATH (12-249): 1.53e-49: 179: 23.14
+	Hs
		474021 PAB4L_HUMAN (136-320): 1.67e-29: 117: 15.14		PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98
+	Hs
		403212 PABP4_HUMAN (230-320): 6.63e-24: 104: 24.18		LA_HUMAN (24-365): 5.96e-44: 163: 18.83
+	Hs
		474033 PAB4L_HUMAN (136-320): 1.67e-29: 117: 15.14		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02
+	Hs
		516339 PABP1_HUMAN (230-320): 3.49e-24: 104: 26.37		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		516495 PABP4_HUMAN (230-320): 6.63e-24: 104: 24.18		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		1031407 PABP4_HUMAN (230-320): 6.63e-24: 104: 24.18		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02
+	Hs
		474034 PAB4L_HUMAN (136-320): 1.67e-29: 117: 15.14		PABP5_HUMAN (12-206): 7.64e-32: 128: 14.15
+	Hs
		1119141 PAP1L_HUMAN (230-319): 2.16e-24: 105: 26.67		PABP5_HUMAN (12-206): 7.64e-32: 128: 14.15
+	Mm
		665745 PABP1_MOUSE (230-320): 3.69e-24: 104: 26.37		TIA1_MOUSE (120-325): 5.06e-24: 106: 13.94
+	Zm
		8143 A0A1D6ELH4_MAIZE (54-320): 4.25e-36: 139: 15.33		A0A1D6ELH4_MAIZE (2-130): 7.34e-12: 70.3: 10.69
+	Hs
		1031367 PABP4_HUMAN (230-320): 6.63e-24: 104: 24.18		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23
+	Hs
		1031344 PABP4_HUMAN (230-320): 6.63e-24: 104: 24.18		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50