HitPredict

Interactor 1: PSD10 (O75832)
26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin) (p28(GANK))
Gene: PSMD10

Interactor 2: PRS6A (P17980)
26S proteasome regulatory subunit 6A (26S proteasome AAA-ATPase subunit RPT5) (Proteasome 26S subunit ATPase 3) (Proteasome subunit P50) (Tat-binding protein 1) (TBP-1)
Gene: PSMC3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.922

The method score is based on:

Property Details
Experiments 17353931, 33961781, 26186194, 28514442, 19490896
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_lid_3~Ank, AAA_lid_3~Ank_2
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 226
Hs

1 439
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Last updated: 15 Jul 2024