Protein: NIPS1
Protein NipSnap homolog 1 (NipSnap1)

Gene: NIPS1, NIPSNAP1
Organism: Homo sapiens
Interactions: 183
UniProt ID: Q9BPW8

Gene Ontology (top 5):
GO:0000423 - mitophagy
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0019233 - sensory perception of pain
GO:0030674 - protein-macromolecule adaptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

276167

NIPS2
Protein NipSnap homolog 2

6

5

High-throughput

0.943

High

1108090

SQSTM
Sequestosome-1

5

4

Small-scale

0.712

High

532901

CH60
60 kDa heat shock protein, mitochondrial

3

5

High-throughput

0.650

High

1162513

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

3

2

Small-scale

0.640

High

952313

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

2

10

High-throughput

0.611

High

1409589

MLP3B
Microtubule-associated protein 1 light chain 3 beta

2

10

Small-scale

0.611

High

1409596

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

2

10

Small-scale

0.611

High

833430

RGS2
Regulator of G-protein signaling 2

2

0

High-throughput

0.594

High

835738

KPCI
Protein kinase C iota type

3

3

High-throughput

0.593

High

1310344

HSC20
Iron-sulfur cluster co-chaperone protein HscB

2

0

High-throughput

0.585

High

242724

PRKN
E3 ubiquitin-protein ligase parkin

2

1

High-throughput

0.584

High

1051299

KPCZ
Protein kinase C zeta type

3

3

High-throughput

0.578

High

328128

GBRAP
Gamma-aminobutyric acid receptor-associated protein

2

10

Small-scale

0.571

High

1123393

ICT1
Large ribosomal subunit protein mL62

2

0

High-throughput

0.559

High

1402097

IF140
Intraflagellar transport protein 140 homolog

1

2

High-throughput

0.536

High

1409592

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

10

High-throughput

0.536

High

1114122

CUL3
Cullin-3

2

1

High-throughput

0.533

High

1128811

NBR1
Next to BRCA1 gene 1 protein

2

1

Small-scale

0.533

High

935060

TERA
Transitional endoplasmic reticulum ATPase

2

1

High-throughput

0.521

High

190164

TNC18
Trinucleotide repeat-containing gene 18 protein

1

0

High-throughput

0.513

High

1409609

RT18A
Large ribosomal subunit protein mL66

1

0

High-throughput

0.513

High

1199669

KLH22
Kelch-like protein 22

2

2

High-throughput

0.504

High

556306

CADH1
Cadherin-1

1

1

Small-scale

0.489

High

610852

TCPA
T-complex protein 1 subunit alpha

1

6

High-throughput

0.489

High

821532

TCPZ
T-complex protein 1 subunit zeta

1

7

High-throughput

0.489

High

876144

TCPE
T-complex protein 1 subunit epsilon

1

7

High-throughput

0.489

High

882117

TCPG
T-complex protein 1 subunit gamma

1

7

High-throughput

0.489

High

899201

TCPQ
T-complex protein 1 subunit theta

1

8

High-throughput

0.489

High

899551

TCPD
T-complex protein 1 subunit delta

1

6

High-throughput

0.489

High

1007229

TCPB
T-complex protein 1 subunit beta

1

8

High-throughput

0.489

High

1131362

GANAB
Neutral alpha-glucosidase AB

1

1

High-throughput

0.489

High

1143243

PLEC
Plectin

1

1

High-throughput

0.489

High

1338248

WDR19
WD repeat-containing protein 19

1

3

High-throughput

0.489

High

1407531

TCPH
T-complex protein 1 subunit eta

1

7

High-throughput

0.489

High

1409630

NS1BP
Influenza virus NS1A-binding protein

1

1

High-throughput

0.489

High

61601

VWA8
von Willebrand factor A domain-containing protein 8

1

2

High-throughput

0.479

High

137795

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

1

High-throughput

0.479

High

275088

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

1

High-throughput

0.479

High

279881

CISY
Citrate synthase, mitochondrial

1

1

High-throughput

0.479

High

282055

MPPB
Mitochondrial-processing peptidase subunit beta

1

1

High-throughput

0.479

High

287358

RF1M
Peptide chain release factor 1, mitochondrial

1

1

High-throughput

0.479

High

326608

MFN2
Mitofusin-2

1

1

High-throughput

0.479

High

412513

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.479

High

471206

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

2

High-throughput

0.479

High

786227

LONM
Lon protease homolog, mitochondrial

1

4

High-throughput

0.479

High

828915

MDHM
Malate dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

856355

IF2M
Translation initiation factor IF-2, mitochondrial

1

3

High-throughput

0.479

High

882842

EFTU
Elongation factor Tu, mitochondrial

1

1

High-throughput

0.479

High

1083718

MPPA
Mitochondrial-processing peptidase subunit alpha

1

1

High-throughput

0.479

High

1087513

GRSF1
G-rich sequence factor 1

1

1

High-throughput

0.479

High

1117816

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

2

High-throughput

0.479

High

1207118

SYAM
Alanine--tRNA ligase, mitochondrial

1

1

High-throughput

0.479

High

1272968

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

1

High-throughput

0.479

High

1290677

ZCH18
Zinc finger CCCH domain-containing protein 18

1

1

High-throughput

0.479

High

1367116

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1381686

FAKD4
FAST kinase domain-containing protein 4

1

1

High-throughput

0.479

High

1382921

S2546
Mitochondrial outer membrane protein SLC25A46

1

1

High-throughput

0.479

High

1383547

MCUR1
Mitochondrial calcium uniporter regulator 1

1

2

High-throughput

0.479

High

1401589

EFGM
Elongation factor G, mitochondrial

1

2

High-throughput

0.479

High

1409588

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

1

High-throughput

0.479

High

1409590

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

2

High-throughput

0.479

High

1409602

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

3

High-throughput

0.479

High

1409606

SIR3
NAD-dependent protein deacetylase sirtuin-3, mitochondrial

1

1

Small-scale

0.479

High

1409607

DDX28
Probable ATP-dependent RNA helicase DDX28

1

3

High-throughput

0.479

High

1409611

OCAD1
OCIA domain-containing protein 1

1

1

High-throughput

0.479

High

1409612

MARH5
E3 ubiquitin-protein ligase MARCHF5

1

1

High-throughput

0.479

High

1409617

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

1

High-throughput

0.479

High

1409627

SAM50
Sorting and assembly machinery component 50 homolog

1

1

Small-scale

0.479

High

183715

RT12
Small ribosomal subunit protein uS12m

1

0

High-throughput

0.458

High

283945

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

1

0

High-throughput

0.458

High

350967

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.458

High

405206

SODM
Superoxide dismutase [Mn], mitochondrial

1

0

Small-scale

0.458

High

505452

CISD3
CDGSH iron-sulfur domain-containing protein 3, mitochondrial

1

0

High-throughput

0.458

High

519208

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

841896

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

852003

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

1024154

TFAM
Transcription factor A, mitochondrial

1

0

High-throughput

0.458

High

1048659

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1058236

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1090511

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

0

High-throughput

0.458

High

1149613

SURF1
Surfeit locus protein 1

1

0

High-throughput

0.458

High

1356863

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

1

0

High-throughput

0.458

High

1386001

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

0

High-throughput

0.458

High

1388248

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.458

High

1388377

MTEF3
Transcription termination factor 3, mitochondrial

1

0

High-throughput

0.458

High

1400802

TEFM
Transcription elongation factor, mitochondrial

1

0

High-throughput

0.458

High

1403396

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.458

High

1409582

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.458

High

1409583

TMM70
Transmembrane protein 70, mitochondrial

1

0

High-throughput

0.458

High

1409584

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

0

High-throughput

0.458

High

1409586

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.458

High

1409587

NMES1
Normal mucosa of esophagus-specific gene 1 protein

1

0

High-throughput

0.458

High

1409595

IF3M
Translation initiation factor IF-3, mitochondrial

1

0

High-throughput

0.458

High

1409601

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

1409605

NGRN
Neugrin

1

0

High-throughput

0.458

High

1409608

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

1409610

MCUB
Calcium uniporter regulatory subunit MCUb, mitochondrial

1

0

High-throughput

0.458

High

1409615

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

1409624

RM11
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.458

High

1409625

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.458

High

1409629

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

0

High-throughput

0.458

High

508517

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

3

High-throughput

0.457

High

1111

SIM26
Small integral membrane protein 26

1

1

High-throughput

0.445

High

530289

TAU
Microtubule-associated protein tau

1

2

High-throughput

0.445

High

1209571

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.445

High

164427

NRP1
Neuropilin-1

1

1

High-throughput

0.437

High

173275

XPO1
Exportin-1

1

1

High-throughput

0.437

High

323553

TRI37
E3 ubiquitin-protein ligase TRIM37

1

5

Small-scale

0.437

High

589525

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

696334

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

769008

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

884387

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

3

Small-scale

0.437

High

897374

CDK7
Cyclin-dependent kinase 7

1

1

High-throughput

0.437

High

933802

DRG2
Developmentally-regulated GTP-binding protein 2

1

1

High-throughput

0.437

High

990982

UBE2B
Ubiquitin-conjugating enzyme E2 B

1

3

Small-scale

0.437

High

1107145

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.437

High

1138557

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.437

High

1151843

RHOH
Rho-related GTP-binding protein RhoH

1

2

High-throughput

0.437

High

1197070

AMOT
Angiomotin

1

1

High-throughput

0.437

High

1255253

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

1278437

HAUS6
HAUS augmin-like complex subunit 6

1

1

High-throughput

0.437

High

1338929

NUP43
Nucleoporin Nup43

1

2

High-throughput

0.437

High

1339675

TNIP2
TNFAIP3-interacting protein 2

1

1

High-throughput

0.437

High

1348190

TIP
T-cell immunomodulatory protein

1

1

High-throughput

0.437

High

1409597

RHOJ
Rho-related GTP-binding protein RhoJ

1

2

High-throughput

0.437

High

1409598

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

1409600

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.437

High

1409614

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

1

Small-scale

0.437

High

1409616

CT2NL
CTTNBP2 N-terminal-like protein

1

1

High-throughput

0.437

High

1409618

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.437

High

1409626

ARI1
E3 ubiquitin-protein ligase ARIH1

1

1

High-throughput

0.437

High

1098747

NDK3
Nucleoside diphosphate kinase 3

1

0

High-throughput

0.426

High

1219260

Q5VY60
HAUS augmin like complex subunit 6

1

1

High-throughput

0.407

High

1293762

PPR3B
Protein phosphatase 1 regulatory subunit 3B

1

1

High-throughput

0.407

High

1323758

S39AB
Zinc transporter ZIP11

1

1

High-throughput

0.407

High

1409585

S12A9
Solute carrier family 12 member 9

1

1

High-throughput

0.407

High

1409620

S39AA
Zinc transporter ZIP10

1

1

High-throughput

0.407

High

1155703

EZH2
Histone-lysine N-methyltransferase EZH2

2

0

High-throughput

0.305

High

1229255

RHG17
Rho GTPase-activating protein 17

2

0

High-throughput

0.298

High

668229

CXCR2
C-X-C chemokine receptor type 2

1

0

Small-scale

0.279

Low

897598

KNTC1
Kinetochore-associated protein 1

1

0

High-throughput

0.279

Low

930784

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

1

0

High-throughput

0.279

Low

1127597

FAT1
Protocadherin Fat 1

1

0

High-throughput

0.279

Low

1204281

DJC21
DnaJ homolog subfamily C member 21

1

0

High-throughput

0.279

Low

1210515

HP1B3
Heterochromatin protein 1-binding protein 3

1

0

High-throughput

0.279

Low

1310019

FXRD2
FAD-dependent oxidoreductase domain-containing protein 2

1

0

High-throughput

0.279

Low

1398150

NSE2
E3 SUMO-protein ligase NSE2

1

0

High-throughput

0.279

Low

1405362

POP1
Ribonucleases P/MRP protein subunit POP1

1

0

High-throughput

0.279

Low

1409581

BCL7B
B-cell CLL/lymphoma 7 protein family member B

1

0

High-throughput

0.279

Low

1409593

ASCC2
Activating signal cointegrator 1 complex subunit 2

1

0

High-throughput

0.279

Low

1409594

IL25
Interleukin-25

1

0

High-throughput

0.279

Low

1409613

ARHGC
Rho guanine nucleotide exchange factor 12

1

0

High-throughput

0.279

Low

1409619

TCF20
Transcription factor 20

1

0

High-throughput

0.279

Low

1409621

HPSE
Heparanase

1

0

High-throughput

0.279

Low

1409622

FND3A
Fibronectin type-III domain-containing protein 3A

1

0

High-throughput

0.279

Low

1409623

ZN281
Zinc finger protein 281

1

0

High-throughput

0.279

Low

1409628

TF3C5
General transcription factor 3C polypeptide 5

1

0

High-throughput

0.279

Low

450345

ACBP
Acyl-CoA-binding protein

1

0

High-throughput

0.265

Low

157782

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

272417

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.249

Low

294238

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

326002

UBR5
E3 ubiquitin-protein ligase UBR5

1

0

Small-scale

0.249

Low

352528

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.249

Low

372970

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.249

Low

377702

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

447361

NPM
Nucleophosmin

1

0

High-throughput

0.249

Low

965192

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.249

Low

1135067

CUL7
Cullin-7

1

0

High-throughput

0.249

Low

1229651

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low

1238794

TECT3
Tectonic-3

1

0

High-throughput

0.249

Low

1323394

FXL14
F-box/LRR-repeat protein 14

1

0

Small-scale

0.249

Low

1339151

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.249

Low

1364553

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.249

Low

1393632

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

1406473

ATX2
Ataxin-2

1

0

High-throughput

0.249

Low

1409591

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.249

Low

1409604

MYO10
Unconventional myosin-X

1

0

Small-scale

0.249

Low

1409603

TBC17
TBC1 domain family member 17

1

0

High-throughput

0.238

Low

564283

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.232

Low

1119276

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.232

Low

1335693

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.232

Low

1395276

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.232

Low

1409599

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025