Interactor 1: PDCD6 (O75340)
Programmed cell death protein 6 (Apoptosis-linked gene 2 protein homolog) (ALG-2)
Gene: PDCD6

Interactor 2: VGFR2 (P35968)
Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)
Gene: KDR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.46 0.60 0.529

The method score is based on:

Property Details
Experiments 21893193
Identification Methods anti bait coimmunoprecipitation, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001525 - angiogenesis
GO:0001938 - positive regulation of endothelial cell proliferation
GO:0005634 - nucleus
GO:0005768 - endosome
GO:0005783 - endoplasmic reticulum
and 3 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 191
Hs

1 1356
+ Hs
+ Hs

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Last updated: 11Aug2025