HitPredict

Interactor 1: STAM2 (O75886)
Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein)
Gene: STAM2

Interactor 2: FGFR2 (P21802)
Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)
Gene: FGFR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_1
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 525 Hs			1 821
+	Hs
		601561 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		FGFR2_HUMAN (1-821): 0: 863: 100.00
+	Hs
		276996 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		FGFR1_HUMAN (1-820): 0: 772: 71.17
+	Hs
		277004 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		FGFR3_HUMAN (10-821): 0: 731: 65.69
+	Hs
		508131 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		FGFR1_HUMAN (1-820): 0: 772: 71.17
+	Hs
		277003 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		FGFR4_HUMAN (22-810): 0: 684: 55.86
+	Hs
		609455 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		FGFR3_HUMAN (10-821): 0: 731: 65.69
+	Hs
		608072 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		FGFR4_HUMAN (22-810): 0: 684: 55.86
+	Hs
		277011 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA3_HUMAN (18-778): 3.24e-168: 514: 18.30
+	Hs
		277037 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA4_HUMAN (18-794): 4.37e-165: 506: 18.60
+	Hs
		277036 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA5_HUMAN (18-766): 3.48e-163: 502: 17.53
+	Hs
		277152 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA6_HUMAN (9-788): 5.01e-162: 499: 17.99
+	Hs
		277073 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		NTRK3_HUMAN (166-765): 7.85e-160: 488: 25.31
+	Hs
		277067 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA7_HUMAN (64-791): 2.59e-157: 486: 19.23
+	Hs
		277010 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA2_HUMAN (18-798): 4.64e-157: 485: 19.21
+	Hs
		277074 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		NTRK2_HUMAN (123-765): 4.81e-153: 469: 23.43
+	Hs
		276988 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		RET_HUMAN (228-816): 2.74e-144: 455: 34.26
+	Hs
		276985 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04
+	Hs
		872470 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		EPHA5_HUMAN (18-766): 3.48e-163: 502: 17.53
+	Hs
		665303 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		EPHA2_HUMAN (18-798): 4.64e-157: 485: 19.21
+	Hs
		385279 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04