HitPredict

Interactor 1: STAM2 (O75886)
Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein)
Gene: STAM2

Interactor 2: EPHA8 (P29322)
Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) (EPH-like kinase 3) (EK3) (hEK3) (Tyrosine-protein kinase receptor EEK)
Gene: EPHA8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_1
Common GO terms	GO:0031901 - early endosome membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 525 Hs			1 1005
+	Hs
		277036 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA5_HUMAN (2-1001): 0: 1242: 57.21
+	Hs
		277067 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA7_HUMAN (5-1005): 0: 1236: 56.16
+	Hs
		277037 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA4_HUMAN (8-1005): 0: 1220: 55.92
+	Hs
		277011 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA3_HUMAN (24-1001): 0: 1208: 55.66
+	Hs
		277152 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA6_HUMAN (1-1005): 0: 1199: 52.23
+	Hs
		665508 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		EPHA8_HUMAN (1-1005): 0: 1245: 100.00
+	Hs
		872470 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		EPHA5_HUMAN (2-1001): 0: 1242: 57.21
+	Hs
		277010 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA2_HUMAN (30-1001): 0: 1097: 46.78
+	Hs
		872497 GGA3_HUMAN (1-510): 1.35e-56: 203: 15.73		EPHA5_HUMAN (2-1001): 0: 1242: 57.21
+	Hs
		665303 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		EPHA2_HUMAN (30-1001): 0: 1097: 46.78
+	Hs
		665436 GGA3_HUMAN (1-510): 1.35e-56: 203: 15.73		EPHA3_HUMAN (24-1001): 0: 1208: 55.66
+	Hs
		665608 ITSN1_HUMAN (188-414): 1.91e-46: 176: 22.50		EPHB2_HUMAN (31-1005): 0: 1211: 49.95
+	Hs
		159899 HGS_HUMAN (135-518): 7.87e-15: 79.4: 10.95		EPHA8_HUMAN (1-1005): 0: 1245: 100.00
+	Hs
		159898 HGS_HUMAN (135-518): 7.87e-15: 79.4: 10.95		EPHA3_HUMAN (24-1001): 0: 1208: 55.66
+	Hs
		159897 HGS_HUMAN (135-518): 7.87e-15: 79.4: 10.95		EPHA2_HUMAN (30-1001): 0: 1097: 46.78
+	Hs
		159843 HGS_HUMAN (135-518): 7.87e-15: 79.4: 10.95		INSR_HUMAN (377-935): 6.29e-143: 463: 25.85
+	Hs
		272788 TM1L1_HUMAN (6-494): 3.07e-63: 215: 16.02		LYN_HUMAN (629-900): 2.17e-59: 214: 41.39
+	Hs
		272786 TM1L1_HUMAN (6-494): 3.07e-63: 215: 16.02		FYN_HUMAN (629-900): 6.44e-59: 213: 41.76
+	Hs
		433753 SPTN1_HUMAN (103-481): 2.5e-55: 202: 14.59		LYN_HUMAN (629-900): 2.17e-59: 214: 41.39
+	Hs
		433781 ITSN1_HUMAN (188-414): 1.91e-46: 176: 22.50		LYN_HUMAN (629-900): 2.17e-59: 214: 41.39