Protein: PLMN
Plasminogen (EC 3.4.21.7) [Cleaved into: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B]

Gene: PLMN, PLG
Organism: Homo sapiens
Interactions: 84
UniProt ID: P00747

Gene Ontology (top 5):
GO:0002020 - protease binding
GO:0004175 - endopeptidase activity
GO:0004252 - serine-type endopeptidase activity
GO:0005102 - signaling receptor binding
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

341349

SPRC
SPARC

2

2

Small-scale

0.812

High

341346

A2AP
Alpha-2-antiplasmin

2

20

Small-scale

0.778

High

341365

CRK
Adapter molecule crk

1

3

High-throughput

0.691

High

341345

MET
Hepatocyte growth factor receptor

1

20

Small-scale

0.665

High

341299

FA10
Coagulation factor X

1

15

Small-scale

0.647

High

341333

APOH
Beta-2-glycoprotein 1

1

6

Small-scale

0.647

High

341338

A4
Amyloid-beta precursor protein

1

17

Small-scale

0.647

High

341339

PAI1
Plasminogen activator inhibitor 1

1

20

Small-scale

0.647

High

341351

CO7
Complement component C7

1

8

Small-scale

0.647

High

341374

PAPP1
Pappalysin-1

1

15

Small-scale

0.647

High

341377

PCOC1
Procollagen C-endopeptidase enhancer 1

1

15

Small-scale

0.647

High

341354

TF
Tissue factor

1

0

Small-scale

0.614

High

341344

TSP1
Thrombospondin-1

2

14

Small-scale

0.602

High

341360

1433T
14-3-3 protein theta

2

3

High-throughput

0.601

High

341332

IGHA1
Immunoglobulin heavy constant alpha 1

1

1

High-throughput

0.575

High

341394

CBPB2
Carboxypeptidase B2

1

4

Small-scale

0.575

High

341358

ATPA
ATP synthase subunit alpha, mitochondrial

1

1

Small-scale

0.561

High

341366

ACTB
Actin, cytoplasmic 1

1

0

Small-scale

0.554

High

341381

AMOT
Angiomotin

1

1

Small-scale

0.552

High

341356

IBP3
Insulin-like growth factor-binding protein 3

1

4

Small-scale

0.550

High

341337

HSPB1
Heat shock protein beta-1

1

1

Small-scale

0.536

High

182992

P2RX6
P2X purinoceptor 6

1

2

High-throughput

0.536

High

341355

AATC
Aspartate aminotransferase, cytoplasmic

1

1

High-throughput

0.536

High

341363

CCR1
C-C chemokine receptor type 1

1

3

High-throughput

0.536

High

341390

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

5

High-throughput

0.536

High

341399

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

4

High-throughput

0.536

High

341353

CH60
60 kDa heat shock protein, mitochondrial

1

0

Small-scale

0.531

High

341404

RHG20
Rho GTPase-activating protein 20

2

5

High-throughput

0.521

High

341408

RHG26
Rho GTPase-activating protein 26

2

2

High-throughput

0.521

High

341361

LYOX
Protein-lysine 6-oxidase

1

0

Small-scale

0.513

High

341362

SC6A1
Sodium- and chloride-dependent GABA transporter 1

1

0

High-throughput

0.513

High

341389

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.513

High

341406

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

0

High-throughput

0.513

High

341350

RAP2A
Ras-related protein Rap-2a

1

3

High-throughput

0.508

High

341331

KNG1
Kininogen-1

1

1

Small-scale

0.501

High

341334

FINC
Fibronectin

1

11

Small-scale

0.501

High

341343

HS90A
Heat shock protein HSP 90-alpha

1

1

Small-scale

0.501

High

341347

HMGB1
High mobility group protein B1

1

3

Small-scale

0.501

High

341357

LAMA1
Laminin subunit alpha-1

1

10

Small-scale

0.501

High

341367

S10AA
Protein S100-A10

1

3

Small-scale

0.501

High

341379

LAMA3
Laminin subunit alpha-3

1

13

Small-scale

0.501

High

341364

DPP6
Dipeptidyl aminopeptidase-like protein 6

1

0

High-throughput

0.493

High

341370

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

1

High-throughput

0.489

High

341384

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

5

High-throughput

0.489

High

341398

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

5

High-throughput

0.489

High

341409

SSUH2
Protein SSUH2 homolog

1

1

High-throughput

0.489

High

341369

SMAD3
Mothers against decapentaplegic homolog 3

1

3

High-throughput

0.481

High

341375

SMAD4
Mothers against decapentaplegic homolog 4

1

3

High-throughput

0.481

High

341378

MK14
Mitogen-activated protein kinase 14

1

1

High-throughput

0.481

High

341395

YTDC1
YTH domain-containing protein 1

1

3

High-throughput

0.481

High

341341

ENOA
Alpha-enolase

1

0

Small-scale

0.480

High

341352

CMGA
Chromogranin-A

1

0

Small-scale

0.480

High

341402

PLRKT
Plasminogen receptor

1

0

Small-scale

0.480

High

226204

PRKN
E3 ubiquitin-protein ligase parkin

1

3

High-throughput

0.479

High

341335

MYCN
N-myc proto-oncogene protein

1

8

High-throughput

0.479

High

341336

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

341340

ATPB
ATP synthase subunit beta, mitochondrial

1

1

Small-scale

0.479

High

341342

ANXA2
Annexin A2

1

1

Small-scale

0.479

High

341359

PTX3
Pentraxin-related protein PTX3

1

2

Small-scale

0.479

High

341371

TF65
Transcription factor p65

1

1

Small-scale

0.479

High

341383

RHG21
Rho GTPase-activating protein 21

1

1

High-throughput

0.479

High

341385

CDC73
Parafibromin

1

1

High-throughput

0.479

High

341386

LMBRL
Protein LMBR1L

1

1

High-throughput

0.479

High

341401

RGAP1
Rac GTPase-activating protein 1

1

2

High-throughput

0.479

High

341380

FX4L6
Forkhead box protein D4-like 6

1

1

High-throughput

0.470

High

341373

PRDX4
Peroxiredoxin-4

1

0

High-throughput

0.460

High

341392

CYFP2
Cytoplasmic FMR1-interacting protein 2

1

0

High-throughput

0.460

High

341348

F16P1
Fructose-1,6-bisphosphatase 1

1

0

High-throughput

0.458

High

341388

MALD2
MARVEL domain-containing protein 2

1

1

Small-scale

0.457

High

298028

UFL1
E3 UFM1-protein ligase 1

1

3

High-throughput

0.437

High

341368

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

6

High-throughput

0.437

High

341393

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.437

High

341396

RING2
E3 ubiquitin-protein ligase RING2

1

3

High-throughput

0.437

High

341400

TRI31
E3 ubiquitin-protein ligase TRIM31

1

3

High-throughput

0.437

High

341407

PKHG1
Pleckstrin homology domain-containing family G member 1

1

2

High-throughput

0.437

High

341397

THIOM
Thioredoxin, mitochondrial

1

2

High-throughput

0.417

High

341382

Q5JYA6
PLEKHG1

1

2

High-throughput

0.407

High

265575

E2F6
Transcription factor E2F6

1

0

High-throughput

0.279

Low

341391

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.279

Low

341403

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

0

High-throughput

0.279

Low

341405

PHF11
PHD finger protein 11

1

0

High-throughput

0.279

Low

341387

RBBP6
E3 ubiquitin-protein ligase RBBP6

1

0

High-throughput

0.265

Low

341372

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.251

Low

341376

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024