HitPredict

Interactor 1: CCNK (O75909)
Cyclin-K
Gene: CCNK

Interactor 2: CDK9 (P50750)
Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)
Gene: CDK9

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.61 1.00 0.783

The method score is based on:

Property Details
Experiments 10574912, 36736316
Identification Methods pull down, two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Cyclin_N~Pkinase
Common GO terms GO:0004693 - cyclin-dependent protein serine/threonine kinase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006366 - transcription by RNA polymerase II
GO:0008024 - cyclin/CDK positive transcription elongation factor complex
and 3 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 580
Hs

1 372
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+ Dm
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+ Sp
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024